Potential of fluoridated carbamide peroxide gels to support post-bleaching enamel re-hardening
Potential of fluoridated carbamide peroxide gels to support post-bleaching enamel re-hardening
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DOI：
10.1016/j.jdent.2007.06.005
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发表时间：
2007-09-01
影响因子：
4.4
通讯作者：
Wiegand, Annette
中科院分区：
文献类型：
--
作者：
Attin, Thomas;Betke, Herbert;Wiegand, Annette
目的：体外研究的目的是评价在每日去矿化和去矿化方案下，用氟化（0.5% F-，以NaF计）和无氟过氧化脲（CP）漂白凝胶漂白后重建釉质表面显微硬度所需的时间。材料与方法：取牛切牙牙釉质标本90个，进行努氏显微硬度测定。将样品分成5组，并使用实验设计的中性和酸性10%CP凝胶漂白7天（每天8小时）：A（0.5%F-，pH 7.0）、B（0.5%F-，pH 5.5）、C（无F-，pH 7.0）和D（无F-，pH 5.5）。E组作为对照，不漂白。在每个8小时的漂白期后，使样品经受去矿化和再矿化方案。在接下来的5天里，标本不漂白，而是储存在人工唾液中8小时，在此期间保持每日去矿化和再矿化循环。在基线、每次漂白间隔后和每天去矿化和再矿化周期完成后进行努氏显微硬度测定。进行重复测量双因素ANOVA统计分析和置信区间比较，以检查漂白后期间的硬度恢复。结果如下：在第7天完成漂白治疗后，观察到所有漂白组的统计学显著硬度损失，与基线相比，硬度降低约7-15%。氟化的凝胶证明比未氟化的凝胶显著更少的硬度损失。在接下来的时间段内，在第8天的第一个去矿化/再矿化周期后（A组）和第9天的第二个8小时再矿化周期后（B组），分别在氟化组（A和B）中观察到从第8天到第12天硬度恢复到基线数据。用未氟化的漂白凝胶C处理的样本的硬度在第10天后恢复到基线值。D组的样品在漂白后5天期间没有显示硬度数据的恢复。结论：氟化10%过氧化脲漂白凝胶支持漂白牙釉质的再硬化，与未氟化凝胶相比，硬度恢复所需的时间更短。(C)2007爱思唯尔有限公司保留所有权利。
Objective: Aim of the in vitro study was to evaluate the time period needed to re-establish enamel surface microhardness after bleaching with fluoridated (0.5% F- as NaF) and unfluoridated carbamide peroxide (CP) bleaching gels under a daily de- and remineralization protocol. Materials and methods: Ninety enamel specimens were prepared from bovine incisors and prepared for Knoop microhardness determination. The samples were divided into five groups and bleached for 7 days (8 h per day) with experimentally designed neutral and acidic 10% CP gels: A (0.5% F-, pH 7.0) B (0.5% F-, pH 5.5), C (no F-, pH 7.0) and D (no F-, pH 5.5). Group E served as control and was not bleached. After each 8-h bleaching period the samples were subjected to a de- and remineralization protocol. In the following 5 days, the specimens were not bleached, but stored in artificial saliva for 8 h instead; the daily de- and remineralization cycles were maintained during this period. Knoop microhardness determinations were conducted at baseline, after each bleaching interval and after completion of each daily de- and remineralization cycle. A repeated measures two-way ANOVA statistical analysis and a comparison of confidence intervals was conducted to check for hardness recovery during the post-bleaching period. Results: After completion of bleaching therapy on day 7 a statistically significant hardness loss was observed for all bleaching groups in the range of about 7-15% hardness reduction as compared to baseline. The fluoridated gels proved significantly less hardness loss than the unfluoridated gels. In the following period, from days 8 to 12 recovery of hardness to baseline data was observed in the fluoridated groups (A and B) after the first de-/remineralization cycle on day 8 (group A) and after the second 8-h remineralization period on day 9 (group B), respectively. Hardness of the specimens treated with the unfluoridated bleaching gel C returned to baseline values after day 10. The samples of group D did not show recover of hardness data during the 5-day post-bleaching period. Conclusion: Fluoridated 10% carbamide peroxide bleaching gels support re-hardening of bleached enamel with a shorter period needed for hardness recover as compared to unfluoridated gels. (C) 2007 Elsevier Ltd. All rights reserved.