LASER DOPPLER MEASUREMENT OF CUTANEOUS BLOOD-FLOW
LASER DOPPLER MEASUREMENT OF CUTANEOUS BLOOD-FLOW
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DOI：
10.1111/1523-1747.ep12507665
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发表时间：
1977-01-01
影响因子：
6.5
通讯作者：
WATKINS, DW
中科院分区：
文献类型：
--
作者：
HOLLOWAY, GA;WATKINS, DW
介绍了一种无创皮肤血流速度测量仪。该系统利用从皮肤微循环中的移动红细胞反向散射的激光的多普勒频移，该频移通过光学外差技术获得。并与~（133）Xe清除法测定正常人前臂皮肤血流量进行了比较。用紫外线日光灯诱导不同程度的太阳红斑，得到了流量的变化。两种方法之间的Y对X线性回归得到的回归系数= 0.89（P < 0.001，n [数量] = 16）。激光多普勒方法似乎代表了一种实用的技术，用于临床评价任何皮肤表面的皮肤血流。
An instrument for noninvasive measurement of cutaneous blood flow velocity is described. The system utilized the Doppler shift of laser light backscattered from moving red blood cells in the cutaneous microcirculation, the shift being obtained by an optical heterodyning technique. Comparison was made between this technique and the 133xenon clearance technique in measuring cutaneous flow in forearms of normal volunteers. Variations in flow were obtained in inducing different degrees of solar erythema with an ultraviolet sunlamp. A Y on X linear regression yielded a regression coefficient = 0.89 (P < 0.001, n [number] = 16) between the 2 methods. The laser Doppler method appeared to represent a practical technique for clinical evaluation of cutaneous blood flow in any skin surface.