Polymorphonuclear cell functions in patients with primary Sjögren's syndrome.

Polymorphonuclear cell functions in patients with primary Sjögren's syndrome.
复制标题

原发性干燥综合征患者的多形核细胞功能。

DOI:
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发表时间:
1988
影响因子:
3.7
通讯作者:
P. Youinou
P. Youinou
中科院分区:
医学4区
文献类型:
--
作者:
Y. Pennec;A. Gentric;J. Jouquan;P. Youinou

文献摘要

被引文献

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对 22 名原发性干燥综合征 (SS) 患者和 45 名健康对照者的多形核 (PMN) 细胞功能进行了评估。干燥综合征患者的粘附力、吞噬作用、化学发光和杀菌能力并未显着降低。 SS 患者的趋化性和趋化性显着降低,并且前者的结果与后者的结果具有良好的相关性。这些观察结果表明,PMN 细胞迁移率的降低可归因于原代细胞异常和血清抑制作用。
Polymorphonuclear (PMN) cell functions were evaluated in twenty-two patients with primary Sjögren's syndrome (SS) and 45 healthy controls. Adherence, phagocytosis, chemiluminescence and bactericidal ability were not significantly reduced in Sjögren's syndrome patients. Chemotaxis and chemokinesis were markedly reduced in SS patients and the results of the former test correlated well with those of the latter. These observations suggest that the decrease in PMN cell mobility is attributable both to a primary cell abnormality and a serum inhibitory effect.