The response properties of the steady antagonistic surround in the mudpuppy retina.
The response properties of the steady antagonistic surround in the mudpuppy retina.
复制标题
泥小狗视网膜中稳定拮抗周围环境的响应特性。
DOI：
10.1113/jphysiol.1978.sp012294
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
F. Werblin
中科院分区：
文献类型：
--
作者：
L. Thibos;F. Werblin
1.双极细胞和神经节细胞对感受野中心闪光的分级反应仅跨越测试强度域的有限部分：90%以上的分级反应范围可以由不同于100到1.2的测试闪光引起。2.在感受野周围有稳定光照的情况下，引起90%的分级反应所需的对数测试强度的绝对水平增加(重置)，但(1)的关系仍然适用。3.感受场周围的每个点在被照亮时，有助于通过随着距离中心的距离呈指数下降的权重来重置所需的中心测试闪光强度。空间常数为0.25 mm。4.当感受野周围完全被照明覆盖时，在大约1000到1.5的环绕强度域上，对于每增加10倍的环绕强度，获得90%的响应范围所需的中心测试闪光强度必须增加大约10倍。环绕的绝对水平和所需的中心测试强度是相互关联的：当接受野周围被完全覆盖时，具有等于环绕强度的强度的测试闪光引起半最大响应。因此，在全场背景下，双极电势保持在其半最大响应电势附近。6.随着周围环境强度和面积的变化，所需中心测试闪光强度的分级重置与水平单元响应的分级增加具有很好的相关性。据推测，在双极细胞和神经节细胞中，当受到环绕光驱动时，具有反应和接受场特性的单位作为神经元间，重新设置所需的测试闪光强度与反应之间的关系。
1. The graded response of bipolar and ganglion cells to test flashes at the receptive field centre, spans only a limited portion of the test intensity domain: more than 90% of the graded response range can be elicited by test flashes differing by less than 100 to 1. 2. In the presence of steady illumination of the receptive field surround, the absolute levels of log test intensities required to elicit 90% of the graded response are increased (reset), but the relation in (1) still applies. 3. Each point in the receptive field surround, when illuminated, contributes to the resetting of the required centre test flash intensities by a weighing that decreases exponentially with distance from the centre. The space constant is 0.25 mm. 4. When the receptive field surround is fully covered with illumination, the centre test flash intensities required to elicit 90% of the response range must be increased by about tenfold for each tenfold increase in surround intensity over a surround intensity domain of about 1000 to 1. 5. The absolute levels of surround and required centre test intensities are inter‐related: when the receptive field surround is fully covered, a test flash with intensity equal to that of the surround elicits a half‐maximal response. Thus, in the presence of a full field background, the bipolar potential is held near its half‐maximum response potential. 6. The graded resetting of the required centre test flash intensities is well correlated with the graded increase in horizontal cell response as the surround intensity and area are varied. It is inferred that units with response and receptive field properties like those of the horizontal cells, when driven by surround illumination, act as interneurones to reset the relationship between required test flash intensity and response in bipolar and ganglion cells.