Deoxyriboside Control and Synchronization of Mitosis

Deoxyriboside Control and Synchronization of Mitosis
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脱氧核糖苷控制和有丝分裂同步

DOI:
10.1038/194682a0
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发表时间:
1962
期刊:
影响因子:
64.8
通讯作者:
N. Xeros
N. Xeros
中科院分区:
综合性期刊1区
文献类型:
--
作者:
N. Xeros

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在寻找简单的生理学方法来阻断随后细胞分裂的同步化的过程中,人们寻找了长期应用的材料,这些材料可以允许核糖核酸(RNA)和蛋白质的合成,但在DNA复制之前立即抑制细胞。在此期间,我使用过量 (2 mM) 胸苷作为封闭同步剂。
IN seeking simple physiological methods for blocking followed by synchronization of cell division, materials were sought which, applied for prolonged periods, permitted synthesis of ribonucleic acid (RNA) and protein but inhibited cells immediately prior to DNA replication. During this I used excess (2 mM) thymidine as a blocking-synchronizing agent.