Flexible and extendible neural interface device based on cooperative multi-chip CMOS LSI architecture
Flexible and extendible neural interface device based on cooperative multi-chip CMOS LSI architecture
复制标题
基于协作多芯片CMOS LSI架构的灵活可扩展的神经接口装置
DOI：
10.1016/j.sna.2005.03.065
复制
发表时间：
2005
影响因子：
4.6
通讯作者：
J. Ohta
中科院分区：
文献类型：
--
作者：
T. Tokuda;Y. Pan;A. Uehara;K. Kagawa;M. Nunoshita;J. Ohta
提出并制作了一种基于大规模集成电路的协同多芯片神经接口器件，用于刺激和记录。所提出的多芯片器件由小型(本设计中为600μm×600μm)智能神经接口单元芯片组成。该单元芯片有九个神经刺激/记录电极和一个单独的控制电路。它不仅可以作为独立的单元工作，还可以与其他单元芯片协同工作。可以将任意数量的单元芯片配置为多芯片神经接口设备。与传统的单芯片体系结构相比，提出的多芯片体系结构具有许多优势，包括轻薄、机械强度、灵活性和可扩展性。这使得多芯片神经接口设备比传统的单芯片设备更适合体内应用。开发了多芯片器件的封装技术。我们为多芯片神经接口器件和与LSI兼容的铂/金叠层凸点电极开发了一种薄而灵活的封装技术。对所制作的多芯片神经接口器件的功能进行了表征，论证了该器件作为随机访问、多点刺激器的可行性。
An LSI-based cooperative multi-chip neural interface device, for stimulation as well as recording, is proposed and fabricated. The proposed multi-chip device consists of small (600μm×600μm in the present design) intelligent neural interface unit chips. The unit chip has nine neural stimulation/recording electrodes and an individual control circuit. It can work not only as a stand-alone unit, but also in cooperation with other unit chips. One can configure any number of the unit chips as a multi-chip neural interface device. Compared to conventional single-chip architecture, the proposed multi-chip architecture has a number of advantages including thinness, mechanical strength, flexibility, and extendibility. That makes the multi-chip neural interface device more suitable for in vivo applications than conventional single-chip devices. Packaging technology for the multi-chip device was also developed. We developed a thin, flexible packaging technique for the multi-chip neural interface device and LSI-compatible Pt/Au stacked bump electrodes. The functions of the fabricated multi-chip neural interface device were characterized and the feasibility of the device as a random-access, multi-site stimulator was demonstrated.
影响因子：
2.3
作者：
Takeuchi, S;Suzuki, T;Fujita, H
通讯作者：
Fujita, H