Relatively Long Survival in Hepatocellular Carcinoma Presenting With Carcinoid Syndrome.
Relatively Long Survival in Hepatocellular Carcinoma Presenting With Carcinoid Syndrome.
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DOI：
10.4021/gr2010.02.171w
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发表时间：
2010-02
影响因子：
1.5
通讯作者：
Charity A
中科院分区：
文献类型：
--
作者：
Nwokediuko SC;Uchenna I;Esther O;Okechukwu O;Augustine O;Charity A
肝细胞癌是尼日利亚最常见的癌症之一。有些患者可能表现出多种副肿瘤综合征。类癌综合征是一种极为罕见的肝细胞癌的表现。一位57岁男性患者以反复出现的面部潮红、腹泻、三尖瓣反流和尿羟基吲哚乙酸（HIAA）水平非常高作为多中心肝病变的首发表现，经组织学证实为肝细胞癌。在增强计算机断层扫描上，病变也表现为动脉血管增生。患者出现症状6年后仍然存活。
Hepatocelluar carcinoma is one of the commonest cancers in Nigeria. Some patients may manifest a variety of paraneoplastic syndromes. Carcinoid syndrome is an extremely rare presentation of hepatocellular carcinoma. A 57-year old man presented with recurrent facial flushing and diarrhea, tricuspid regurgitation, and very high level of urinary hydroxyindoleacetic acid (HIAA) as the first manifestation of a multicentric hepatic lesion which proved histologically to be hepatocellular carcinoma. The lesions also exhibited arterial hypervascularization on contrast enhanced computerized tomography. The patient is still alive after 6 years of symptoms.