Systolic blood pressure response to exercise stress test and risk of stroke
Systolic blood pressure response to exercise stress test and risk of stroke
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DOI：
10.1161/hs0901.095395
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发表时间：
2001-09-01
期刊：
影响因子：
8.3
通讯作者：
Salonen, JT
中科院分区：
文献类型：
--
作者：
Kurl, S;Laukkanen, JA;Salonen, JT
背景和目的：运动时的收缩压（SBP）被发现可以预测未来高血压、冠心病和心血管疾病死亡的诊断。目前尚无研究显示运动试验期间SBP与卒中之间的关系。本研究的目的是研究收缩压上升，运动后2分钟的最大收缩压百分比之间的关联，并在人口为基础的样本的男性没有先前的冠心病艾德中风的风险。方法收缩压测量期间和运动试验后每2分钟。受试者是一个基于人群的样本，包括1026名基线时无临床冠心病、抗高血压药物或既往卒中的男性。在平均10.4年的随访中，有46例中风（38例缺血性中风）。结果：与收缩压升高>19.7 mm Hg/min的男性相比，收缩压升高>19.7 mm Hg/min的男性发生任何中风的风险增加2.3倍，缺血性中风的风险增加2.3倍。
Background and Purpose-Systolic blood pressure (SBP) during exercise has been found to predict a future diagnosis of hypertension, coronary heart disease, and cardiovascular disease death. No studies have been conducted to show a relationship between SBP during exercise test and stroke. The aim of the present study was to study the associations between SBP rise, percent maximum SBP at 2 minutes after exercise, and the risk of stroke in a population-ba ed sample of men with no prior coronary heart disease.Methods-SBP was measured every 2 minutes during and after the exercise test. The subjects were a population-based sample of 1026 men without clinical coronary heart disease, antihypertensive medication, or prior stroke at baseline. During an average follow-up of 10.4 years, there were 46 cases of stroke (38 ischemic strokes).Results-Men with SBP rise >19.7 mm Hg per minute of exercise duration had a 2.3-fold increased risk of any stroke and a 2.3-fold increased risk of ischemic stroke compared with men whose SBP rise was