Biodegradable MnO2 nanosheet mediated hybridization chain reaction for imaging of human apurinic/apyrimidinic endonuclease 1 activity in living cells
Biodegradable MnO2 nanosheet mediated hybridization chain reaction for imaging of human apurinic/apyrimidinic endonuclease 1 activity in living cells
复制标题
可生物降解的 MnO2 纳米片介导的杂交链式反应，用于活细胞中人脱嘌呤/脱嘧啶核酸内切酶 1 活性的成像
作者：
Li Guangli;Li Junjie;Li Qing
建立了一种检测无嘌呤/无嘧啶内切酶1活性的高灵敏度无酶扩增方法。通过掺入可生物降解的二氧化锰纳米片，实现了原位点亮细胞内ape1活性。
A highly sensitive enzyme-free amplification assay for the detection of apurinic/apyrimidinic endonuclease 1 activity was developed. By incorporating biodegradable MnO2 nanosheets, in situ light up intracellular APE 1 activity was achieved.