Intravenous contrast injection significantly affects bone mineral density measured on CT
Intravenous contrast injection significantly affects bone mineral density measured on CT
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DOI：
10.1007/s00330-014-3408-2
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发表时间：
2015-02-01
影响因子：
5.9
通讯作者：
de Jong, Pim A.
中科院分区：
文献类型：
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作者：
Pompe, Esther;Willemink, Martin J.;de Jong, Pim A.
目的通过对比CT平扫和增强扫描，评价静脉注射造影剂对骨密度（BMD）的影响（99例无恶性肿瘤，53例有恶性肿瘤），均接受了未增强和两次增强扫描纳入了2011年6月至2013年7月期间单次（动脉期和门静脉期）腹部CT检查。结果腰椎CT增强后各期的骨密度值均明显高于平扫期（P <0.05），增强后各期的骨密度值均明显高于平扫期（P <0.05），增强后各期的骨密度值均明显高于平扫期（P <0.05）。
Objective The objective is to evaluate the effect of intravenous contrast media on bone mineral density (BMD) assessment by comparing unenhanced and contrast-enhanced computed tomography (CT) examinations performed for other indications.Methods One hundred and fifty-two patients (99 without and 53 with malignant neoplasm) who underwent both unenhanced and two contrast-enhanced (arterial and portal venous phase) abdominal CT examinations in a single session between June 2011 and July 2013 were included. BMD was evaluated on the three examinations as CT-attenuation values in Hounsfield Units (HU) in the first lumbar vertebra (L1).Results CT-attenuation values were significantly higher in both contrast-enhanced phases, compared to the unenhanced phase (p