FACIAL RECEPTIVE-FIELDS OF TRIGEMINAL NEURONS - INCREASED SIZE FOLLOWING ESTROGEN-TREATMENT IN FEMALE RATS
FACIAL RECEPTIVE-FIELDS OF TRIGEMINAL NEURONS - INCREASED SIZE FOLLOWING ESTROGEN-TREATMENT IN FEMALE RATS
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DOI：
10.1159/000122389
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发表时间：
1975-01-01
影响因子：
4.1
通讯作者：
BARKER, DJ
中科院分区：
文献类型：
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作者：
BEREITER, DA;BARKER, DJ
为了评估以前的报告，扩大生殖器的感觉领域雌激素治疗后的一般性，面部接受领域的个别三叉神经节神经元从卵巢切除雌性大鼠注射雌激素进行了比较，从noninjected控制领域。机械感受野边界用一系列直径不同的刺激探针确定，并根据弯曲点处传递的力进行校准（Von Frey技术）。对于每个单个单元，阈值感受野用能够可靠地激活单个单元放电的最小刺激探针确定。雌激素治疗的女性面部感受野显着大于领域（10倍）比noninjected控制。此外，视野面积的增加与面部区域内的空间位置无关（通常，视野大小从身体躯干的近端-远端方向减小），并且不受切断三叉神经根的影响。接受领域的阈值也显着降低雌激素治疗。长期全身雌激素治疗会影响雌性面部区域的触觉感觉场，这一事实表明，这种现象并不是雄性在交配期间通常接触的生殖器区域所特有的。
In order to assess the generality of previous reports of enlarged genital sensory fields following estrogen treatment, facial receptive fields of individual trigeminal ganglion neurons from ovariectomized female rats injected with estrogen were compared with fields from noninjected controls. Mechanoreceptive field boundaries were determined with a series of stimulating probes varying in diameter, and calibrated according to the force delivered at the bending point (Von Frey technique). For each single unit, the threshold receptive field was determined with the smallest stimulus probe capable of reliably activating single unit discharges. Facial receptive fields from estrogen-treated females were significantly larger in area (by a factor of 10) than fields from noninjected controls. Furthermore, the increase in field area was independent of spatial location within the facial region (normally, field size decreases in a proximal-distal direction from the body trunk), and was not affected by cutting the trigeminal nerve root. Receptive field thresholds were also significantly lowered by estrogen treatment. The fact that long-term systemic estrogen treatment influences tactile sensory fields in the facial region of females suggests that this phenomenon is not peculiar to the genital region normally contacted by the male during mating.