Four "lessons learned" while implementing a multi-site caries prevention trial.
Four "lessons learned" while implementing a multi-site caries prevention trial.
复制标题
实施多地点防龋试验时的四个“经验教训”。
DOI：
10.1111/j.1752-7325.2010.00167.x
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发表时间：
2010
影响因子：
2.3
通讯作者：
X-ACTCollaborativeResearchGroup
中科院分区：
文献类型：
--
作者：
Bader,JamesD;Robinson,DebbieS;Gilbert,GreggH;Ritter,AndreV;Makhija,SoniaK;Funkhouser,KimberlyA;Amaechi,BennettT;Shugars,DanielA;Laws,Reesa;X-ACTCollaborativeResearchGroup
As the number of dental‐related randomized clinical trials (RCTs) increases, there is a need for literature to help investigators inexperienced in conducting RCTs design and implement studies. This commentary describes four “lessons learned” or considerations important in the planning and initial implementation of RCTs in dentistry that, to our knowledge, have not been discussed in the general dental literature describing trial techniques. These considerations are a) preparing or securing a thorough systematic review; b) developing a comprehensive set of study documents; c) designing and testing multiple recruitment strategies; and d) employing a run‐in period prior to enrollment. Attention to these considerations in the planning phases of a dental RCT can help ensure that the trial is clinically relevant while also maximizing the likelihood that its implementation will be successful.
