The Y-chromosome haplogroup C3*-F3918, likely attributed to the Mongol Empire, can be traced to a 2500-year-old nomadic group
The Y-chromosome haplogroup C3*-F3918, likely attributed to the Mongol Empire, can be traced to a 2500-year-old nomadic group
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DOI：
10.1038/s10038-017-0357-z
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发表时间：
2017-12
影响因子：
3.5
通讯作者：
Ye Zhang;Xiyan Wu;Jiawei Li;Hongjie Li;Yongbin Zhao;Hui Zhou
中科院分区：
文献类型：
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作者：
Ye Zhang;Xiyan Wu;Jiawei Li;Hongjie Li;Yongbin Zhao;Hui Zhou
蒙古帝国在塑造现代人口的景观方面发挥了重要作用。生活在欧亚大陆的许多人口可能是蒙古帝国扩张后，古代蒙古人与土著人口混合的产物。遗传学家发现，这些人群中的大多数携带Y单倍群C3*（C-M217）。为了追溯单倍群（Hg）C3* 的历史，进一步了解蒙古族的起源和发展，对来自东胡、鲜卑和室韦三个地区的井沟子、陈屋沟和岗嘎遗址的古人类遗骸进行了分析。结果表明，岗嘎站11名男性中有9名、成武沟站8名男性中有2名、井沟子站12名男性中均存在M130（Hg C）、M217（Hg C3）、L1373（Hg C）突变（C2b，ISOGG 2015），在M93（Hg C3 a）、P39（Hg C3 b）、M48（Hg C3 c）、M407（Hg C3 d）和P62（Hg C3 f）处不存在突变。这些样本归因于Y染色体Hg C3*（Hg C2b，ISOGG 2015），其中大部分基于F3918处的突变进一步分型为Hg C2b 1a。最后，我们推测Y染色体HgC 3 *-F3918可能起源于东胡古代游牧民族。
The Mongol Empire had a significant role in shaping the landscape of modern populations. Many populations living in Eurasia may have been the product of population mixture between ancient Mongolians and natives following the expansion of Mongol Empire. Geneticists have found that most of these populations carried the Y-haplogroup C3* (C-M217). To trace the history of haplogroup (Hg) C3* and to further understand the origin and development of Mongolians, ancient human remains from the Jinggouzi, Chenwugou and Gangga archaeological sites, which belonged to the Donghu, Xianbei and Shiwei, respectively, were analysed. Our results show that nine of the eleven males of the Gangga site, two of the eight males of Chengwugou site and all of the twelve males of Jinggouzi site were found to have mutations at M130 (Hg C), M217 (Hg C3), L1373 (C2b, ISOGG2015), with the absence of mutations at M93 (Hg C3a), P39 (Hg C3b), M48 (Hg C3c), M407 (Hg C3d) and P62 (Hg C3f). These samples were attributed to the Y-chromosome Hg C3* (Hg C2b, ISOGG2015), and most of them were further typed as Hg C2b1a based on the mutation at F3918. Finally, we inferred that the Y-chromosome Hg C3*-F3918 can trace its origins to the Donghu ancient nomadic group.