Effects of astragalus polysaccharides on immunologic function of erythrocyte in chickens infected with infectious bursa disease virus
Effects of astragalus polysaccharides on immunologic function of erythrocyte in chickens infected with infectious bursa disease virus
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DOI：
10.1016/j.vaccine.2010.06.025
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发表时间：
2010-08-02
期刊：
影响因子：
5.5
通讯作者：
Li, Hongquan
中科院分区：
文献类型：
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作者：
Jiang, Junbing;Wu, Caihong;Li, Hongquan
将160只25日龄传染性法氏囊病病毒(IBDV)抗体阴性的海兰白鸡随机分为4组。第2-4组在26日龄时接种0.3mlIBDV。第3组和第4组从感染第1天起分别注射5 mg和10 mg黄芪多糖(APS)，连续6天。分别于21、29、32、35和38日龄心脏采血，测定红细胞-C-3b受体花环率(E-C3bRR)、红细胞-C-3b免疫复合物花环率(E-ICRR)、红细胞花环增强率(ERER)和红细胞花环抑制率(ERIR)。结果表明，雏鸡感染IBDV后，E-C3bRR和ERER显著降低(p
160 Haline white chickens at 25 days old, negative for antibody to infectious bursa disease virus (IBDV), were randomly allocated into four groups. Chickens in groups 2-4 were infected with 0.3 ml IBDV at 26 days old. Chickens in groups 3 and 4 were injected respectively with 5 and 10 mg astragalus polysaccharide (APS) for 6 consecutive days from the first day of infection. At 21, 29, 32, 35 and 38 days old, the blood samples were taken from heart, and erythrocyte-C-3b receptor rosette rate (E-C3bRR), erythrocyte-C-3b immune complex rosette rate (E-ICRR), erythrocyte rosette forming enhancing rate (ERER) and erythrocyte rosette forming inhibitory rate (ERIR) were measured. The results showed that E-C3bRR and ERER significantly declined in chicken infected with IBDV (p