Glucagonomas
Glucagonomas
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DOI：
10.1016/s0950-3528(96)90019-6
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发表时间：
1996-12-01
期刊：
影响因子：
--
通讯作者：
Bloom, SR
中科院分区：
文献类型：
--
作者：
Frankton, S;Bloom, SR
胰高血糖素瘤是一种罕见的，具有挑战性，但可治疗的疾病，具有不同的表现。尽管其主要是恶性的性质，延长无瘤生存期可以实现有针对性的手术，肝动脉栓塞和生长抑素类似物的组合。鉴于管理问题的困难，在有经验的三级转诊中心进行初步评估也可能有好处。本章对18名此类患者进行了长达25年的长期随访。鉴于肿瘤的罕见性，数量很少，但可以从这些患者的临床管理研究中吸取宝贵的经验教训。
Glucagonoma is an uncommon, challenging but treatable disease with varied manifestations. Despite its predominantly malignant nature, prolonged symptom-free survival can be achieved using a targeted combination of surgery, hepatic artery embolization and somatostatin analogues. Given the difficult management issues, an initial assessment in an experienced tertiary referral centre may also be of benefit. This chapter has looked at the long-term follow-up of 18 such patients over a 25-year period. Given the rarity of the tumour, the numbers are small, but valuable lessons can be learnt from the study in the clinical management of these patients.