Cohort Profile: The Social Environment and Biomarkers of Aging Study (SEBAS) in Taiwan
Cohort Profile: The Social Environment and Biomarkers of Aging Study (SEBAS) in Taiwan
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DOI：
10.1093/ije/dyu179
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发表时间：
2016-02-01
影响因子：
7.7
通讯作者：
Weinstein, Maxine
中科院分区：
文献类型：
--
作者：
Cornman, Jennifer C.;Glei, Dana A.;Weinstein, Maxine
社会环境与老化生物标记研究（SEBAS）是一项具有全国代表性的台湾中老年人纵向调查。它将生物标志物和表现评估的收集添加到台湾老龄化纵向研究（TLSA）中，这是一项针对60岁及以上成年人的全国代表性研究，包括制度化人口。TLSA始于1989年，大约每3年随访一次; 1996年和2003年增加了年轻的复习队列。2000年进行了第一波SEBAS，以1999年TLSA的子样本为基础。共有1023名受访者完成了面对面的家庭访谈，几周后又完成了医院体检。除了前一天晚上采集的12小时（晚上7点到早上7点）尿液样本和检查期间采集的空腹血液样本外，训练有素的工作人员还测量了血压、身高、体重、腰围和臀围。2006年进行了第二波SEBAS，采用了与SEBAS 2000类似的程序，但增加了由访谈员在家庭访谈结束时进行的业绩评估。两波SEBAS还包括健康状况（身体，情绪，认知），健康行为，社会关系和暴露于压力源的措施。SEBAS数据可在[ ext-link-type=“uri”http://www.icpsr.umich.edu/icpsrweb/NACDA/studies/3792/version/5“http：//www.icpsr.umich.edu/icpsrweb/NACDA/studies/3792/version/5]上公开查阅，使研究人员能够探索生活挑战、社会环境和健康之间的关系，并审查生物措施和健康变化的前因、相关因素和后果。
The Social Environment and Biomarkers of Aging Study (SEBAS) is a nationally representative longitudinal survey of Taiwanese middle-aged and older adults. It adds the collection of biomarkers and performance assessments to the Taiwan Longitudinal Study of Aging (TLSA), a nationally representative study of adults aged 60 and over, including the institutionalized population. The TLSA began in 1989, with follow-ups approximately every 3 years; younger refresher cohorts were added in 1996 and 2003. The first wave of SEBAS, based on a sub-sample of respondents from the 1999 TLSA, was conducted in 2000. A total of 1023 respondents completed both a face-to-face home interview and, several weeks later, a hospital-based physical examination. In addition to a 12-h (7 pm-7 am) urine specimen collected the night before and a fasting blood specimen collected during the examination, trained staff measured blood pressure, height, weight and waist and hip circumferences. A second wave of SEBAS was conducted in 2006 using a similar protocol to SEBAS 2000, but with the addition of performance assessments conducted by the interviewers at the end of the home interview. Both waves of SEBAS also included measures of health status (physical, emotional, cognitive), health behaviours, social relationships and exposure to stressors. The SEBAS data, which are publicly available at [ ext-link-type="uri" http://www.icpsr.umich.edu/icpsrweb/NACDA/studies/3792/version/5" http://www.icpsr.umich.edu/icpsrweb/NACDA/studies/3792/version/5], allow researchers to explore the relationships among life challenges, the social environment and health and to examine the antecedents, correlates and consequences of change in biological measures and health.