Does informing people who inject drugs of their hepatitis C status influence their injecting behaviour? Analysis of the Networks II study
Does informing people who inject drugs of their hepatitis C status influence their injecting behaviour? Analysis of the Networks II study
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DOI：
10.1016/j.drugpo.2013.08.005
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发表时间：
2014-01-01
影响因子：
4.4
通讯作者：
Hellard, M. E.
中科院分区：
文献类型：
--
作者：
Aspinall, E. J.;Weir, A.;Hellard, M. E.
背景：注射毒品（PWID）的人有感染丙型肝炎病毒（HCV）的风险。这是合理的，PWID谁收到丙型肝炎病毒的诊断将减少他们的注射风险的关注，他们的注射合作伙伴，虽然这方面的证据目前是有限的。本研究的目的是调查是否告知PWID他们的HCV诊断与注射behavior.Methods的变化：前瞻性，纵向研究PWID招募街头毒品市场横跨墨尔本，澳大利亚。每3个月进行一次访谈和HCV检测。之间的关联接受诊断的HCV和（i）注射频率和（ii）注射设备的借款，进行了检查，使用广义估计方程（GEE）analysis.Results：35个人在研究期间接受了诊断的HCV。接受HCV诊断与每月0.35次注射的减少有关（p = 0.046），但注射设备的借用没有变化（p = 0.750）。结论：接受HCV诊断的PWID中观察到注射频率的小幅降低。这一发现应在更大规模的研究中进一步调查，研究更广泛的注射风险行为。(C)2013爱思唯尔有限公司版权所有。
Background: People who inject drugs (PWID) are at risk of hepatitis C virus (HCV). It is plausible that PWID who receive a diagnosis of HCV will reduce their injecting risk out of concern for their injecting partners, although evidence for this is currently limited. The aim of this study was to investigate whether informing PWID of their HCV diagnosis was associated with a change in injecting behaviour.Methods: Prospective, longitudinal study of PWID recruited from street drug markets across Melbourne, Australia. Interviews and HCV testing were conducted at 3-monthly intervals. The association between receiving a diagnosis of HCV and (i) injecting frequency and (ii) injecting equipment borrowing, was examined using generalized estimating equations (GEE) analysis.Results: Thirty-five individuals received a diagnosis of HCV during the study period. Receiving a diagnosis of HCV was associated with a decrease of 0.35 injections per month (p = 0.046) but there was no change in injecting equipment borrowing (p = 0.750).Conclusions: A small reduction in injecting frequency was observed in PWID who received a diagnosis of HCV. This finding should be investigated further in larger studies examining a wider range of injecting risk behaviours. (C) 2013 Elsevier B.V. All rights reserved.