Predicting the holistic force-displacement relation of the periodontal ligament: in-vitro experiments and finite element analysis.
Predicting the holistic force-displacement relation of the periodontal ligament: in-vitro experiments and finite element analysis.
复制标题
DOI：
10.1186/1475-925x-13-107
复制
发表时间：
2014-07-30
影响因子：
3.9
通讯作者：
Lin TS
中科院分区：
文献类型：
--
作者：
Chang CH;Lei YN;Ho YH;Sung YH;Lin TS
牙周膜的生物力学特性在口腔修复学中具有重要意义。本研究的目的是评估的可行性，测量牙周膜的生物力学行为，使用微型计算机断层扫描（micro-CT）。一个定制的装置测量的力和位移的猪PDL标本内的micro-CT环境。同步计算机断层扫描（CT）图像被用来获得整个标本的变形和位移，并重建三维网格模型。为了与实验结果相匹配，然后应用有限元分析来模拟PDL的生物力学响应。在本研究中，PDL的力学模型被假定为超弹性材料。牙齿和牙槽骨的体积变化小于1%，这意味着牙齿位移主要是由PDL的位移引起的。由于从CT图像配准中获得的变换矩阵相同，因此在每个载荷步骤中仅观察到平移位移。力-位移曲线揭示了PDL的非线性行为。实验位移结果与模拟位移结果之间有很高的相关性。数值计算结果（基于PDL是超弹性材料的假设）与实验结果吻合良好。通过micro-CT的非破坏性测量获得PDL的生物力学行为。采用超弹性本构模型可以较好地预测加载后PDL的力-位移关系。本研究为牙周膜的生物力学性能测试提供了一种可行的方法。
The biomechanical property of the periodontal ligament (PDL) is important in orthodontics and prosthodontics. The objective of this study was to evaluate the feasibility of measuring the biomechanical behavior of the periodontal ligament using micro-computed tomography (micro-CT). A custom-made apparatus measured the force and displacement of a porcine PDL specimen within the micro-CT environment. Synchronized computed tomography (CT) images were used to obtain the deformation and displacement of the entire specimen and to reconstruct the three-dimensional mesh model. To match the experimental results, finite element analysis was then applied to simulate the biomechanical response of the PDL. The mechanical model of the PDL was assumed as the hyperelastic material in this study. The volume variations of the tooth and the alveolar bone were less than 1%, which implies that tooth displacement was caused mostly by displacement of the PDL. Only translational displacement was observed with each load step because the transformation matrix acquired from the CT image registration was identical. The force-displacement curve revealed the nonlinear behavior of the PDL. There was a high correlation between the experimental displacement results and the simulation displacement results. The numerical results (based on the assumption that the PDL is the hyperelastic material) showed good agreement with the experimental results. Nondestructive measurements by micro-CT obtained the biomechanical behavior of the PDL. Using the hyperelastic characteristic as the constitutive model can properly predict the force-displacement relation of the PDL after loading. This study provided a feasible approach for measuring the biomechanical behavior of the PDL for further dental application.