Simplified staging for hepatocellular carcinoma
Simplified staging for hepatocellular carcinoma
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DOI：
10.1200/jco.2002.20.6.1527
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发表时间：
2002-03-15
影响因子：
45.3
通讯作者：
Nagorney, DM
中科院分区：
文献类型：
--
作者：
Vauthey, JN;Lauwers, GY;Nagorney, DM
目的：目前的美国癌症联合委员会（AJCC）肝细胞癌（HCC）分期系统不能充分地对患者的预后进行分层。目前提出的肿瘤（T）分类的能力，有效地分层的生存557例患者接受了完全切除的肝癌在四个中心进行了检查。独立的生存预测因素被合并到一个新的分期system.Results：使用目前的AJCC T分类，T1和T2肿瘤患者有相似的5年生存率（P= 0.6）。此外，多发性双叶肿瘤患者（T4）的生存率与T3患者相匹配（P= 0.5）。死亡的独立预测因素是大血管侵犯（P
Purpose: The current American Joint Committee on Cancer (AJCC) staging system for hepatocellular carcinoma (HCC) fails to stratify patients adequately with respect to prognosis.Patients and Methods. The ability of the currently proposed tumor (T) categories to effectively stratify the survival of 557 patients who underwent complete resection for HCC at four centers was examined. Independent predictors of survival were combined into a new staging system.Results: Using the current AJCC T classification, patients with T1 and T2 tumors had similar 5-year survivals (P=.6). In addition, the survival of patients with multiple bilobar tumors (T4) matched that of T3 patients (P=.5). Independent predictors of death were major vascular invasion (P