Neuroprotection mediated by natural products and their chemical derivatives.
Neuroprotection mediated by natural products and their chemical derivatives.
复制标题
天然产物及其化学衍生物介导的神经保护
DOI:
10.4103/1673-5374.282240
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发表时间:
2020-11
影响因子:
6.1
通讯作者:
Fei Z
中科院分区:
文献类型:
--
作者:
Fei F;Su N;Li X;Fei Z
Neuronal injuries can lead to various diseases such as neurodegenerative diseases, stroke, trauma, ischemia and, more specifically, glaucoma and optic neuritis. The cellular mechanisms that regulate neuronal death include calcium influx and calcium overload, excitatory amino acid release, oxidative stress, inflammation and microglial activation. Much attention has been paid to the effective prevention and treatment of neuroprotective drugs by natural products. This review summarizes the neuroprotective aspects of natural products, extracted from Panax ginseng, Camellia sinensis, soy and some other plants, and some of their chemical derivatives. Their antioxidative and anti-inflammatory action and their inhibition of apoptosis and microglial activation are assessed. This will provide new directions for the development of novel drugs and strategies to treat neurodegenerative diseases.
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影响因子:
6.1
作者:
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通讯作者:
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影响因子:
5.3
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Ganguly U;Chakrabarti SS;Kaur U;Mukherjee A;Chakrabarti S
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Chakrabarti S
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Jang YS
影响因子:
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An, Zhen;Qi, Yongmei;Zhang, Yingmei
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Zhang, Yingmei
DOI:
10.1007/s11626-015-9983-y
发表时间:
2016-03-01
影响因子:
2.1
作者:
Ahn, Sungeun;Siddiqi, Muhammad Hanif;Yang, Deok-Chun
通讯作者:
Yang, Deok-Chun