Generation of functionalized aryl and heteroaryl aluminum reagents by halogen-lithium exchange
Generation of functionalized aryl and heteroaryl aluminum reagents by halogen-lithium exchange
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DOI：
10.1039/c3cc43356k
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发表时间：
2013-01-01
影响因子：
4.9
通讯作者：
Knochel, Paul
中科院分区：
文献类型：
--
作者：
Klatt, Thomas;Groll, Klaus;Knochel, Paul
通过在 i-Bu2AlCl 存在下与相应的不饱和有机卤化物进行 I-Li 或 Br-Li 交换反应，得到各种功能化的芳基和杂芳基铝试剂。通过适当的催化剂，将所得的新铝物质直接酰化、烯丙基化或芳基化。烯酮的 1,4-迈克尔加成也已实现。
Various functionalized aryl and heteroaryl aluminum reagents were obtained by performing I-Li or Br-Li exchange reactions with the corresponding unsaturated organic halides in the presence of i-Bu2AlCl. By means of an appropriate catalyst, the resulting new aluminum species were directly acylated, allylated or arylated. 1,4-Michael additions to enones have also been achieved.