Selective photothermal ablation of tissue with a fiber-delivered Er:YAG laser

Selective photothermal ablation of tissue with a fiber-delivered Er:YAG laser
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使用光纤传输的 Er:YAG 激光选择性光热消融组织

DOI:
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发表时间:
1999
期刊:
Biomedical optics
影响因子:
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通讯作者:
H. Devlin
H. Devlin
中科院分区:
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文献类型:
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作者:
M. Pierce;M. Dickinson;H. Devlin

文献摘要

被引文献

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研究了在脉冲Er:YAG激光光热消融过程中,利用激光诱导光电子发射信号区分生物组织软硬的可行性。时间分辨发射光谱表明,约35 J/cm 2的阈值能量密度,定期启动从牙釉质的光发射,而没有发射检测到猪肌肉组织与入射激光能量密度高达约140 J/cm 2。发射信号相对于入射的烧蚀性Er:YAG激光脉冲的延迟时间被发现从发射阈值能量密度附近的约150微秒减小到所使用的最高能量密度水平处的约60微秒。光学多通道分析仪光谱的Er:YAG照射的釉质表明,光电发射通常由一个广泛的,连续的背景在可见光区,与叠加的峰所产生的元素,包括钙的存在下,从样品表面或排放羽流的等离子体发射的特性。
The feasibility of using laser-induced photoemission signals to distinguish between hard and soft biological tissues during photothermal ablation with a pulsed Er:YAG laser has been investigated. Time-resolved emission spectroscopy indicated a threshold fluence of approximately 35 J/cm2 to regularly initiate photoemission from dental enamel, while no emission was detected from porcine muscle tissue with incident laser fluences of up to approximately 140 J/cm2. The delay time of an emission signal with respect to the incident, ablative Er:YAG laser pulse was found to decrease from approximately 150 microseconds near the emission threshold fluence to approximately 60 microseconds at the highest fluence level used. Optical multichannel analyzer spectroscopy of Er:YAG irradiated enamel demonstrated that photoemissions typically consisted of a broad, continuous background in the visible region, with superimposed peaks arising from the presence of elements including calcium, characteristic of plasma emission either from the sample surface or emission plume.