Pulmonary blood flow distribution measured by radionuclide-computed tomography.
Pulmonary blood flow distribution measured by radionuclide-computed tomography.
复制标题
通过放射性核素计算机断层扫描测量肺血流分布。
DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
K. Torizuka
中科院分区：
文献类型：
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作者：
H. Maeda;H. Itoh;Y. Ishii;G. Todo;T. Mukai;M. Fujita;H. Kambara;C. Kawai;K. Torizuka
通过放射性核素-计算机断层扫描，对静脉注射99mtc标记的人血清白蛋白大聚集体，测量了俯卧位、仰卧位和坐位受试者单位肺容量的肺血流分布。除1例二尖瓣严重狭窄外，其余31例受试者的重力方向血流量均较大。当受试者处于坐姿时，可以区分出四种不同的分布类型。一种类型有三个区域的血流分布，如以前报道的韦斯特和同事(J.阿普尔。物理学报。19:713-724,1964)。17例仰卧位患者和2例坐位患者的肺动脉压和静脉压与Swan-Ganz导管测得的肺动脉压和毛细血管楔压基本一致。该方法使无创评估肺血管压力成为可能。
Distributions of pulmonary blood flow per unit lung volume were measured with subjects in the prone, supine, and sitting positions by means of radionuclide-computed tomography of intravenously administered 99mTc-labeled macroaggregates of human serum albumin. The blood flow was greater in the direction of gravity in all 31 subjects except one with severe mitral valve stenosis. With the subject in a sitting position, four different types of distribution were distinguished. One type had a three-zonal blood flow distribution as previously reported by West and co-workers (J. Appl. Physiol. 19: 713-724, 1964). Pulmonary arterial pressure and venous pressure estimated from this model showed reasonable agreement with pulmonary arterial pressure and capillary wedge pressure measured by Swan-Ganz catheter in 17 supine patients and in 2 sitting patients. The method makes possible noninvasive assessment of pulmonary vascular pressures.