4-Sulfotetrafluorophenyl (STP) esters: New water-soluble amine-reactive reagents for labeling biomolecules
4-Sulfotetrafluorophenyl (STP) esters: New water-soluble amine-reactive reagents for labeling biomolecules
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DOI：
10.1016/s0040-4039(98)02695-1
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发表时间：
1999-02-19
影响因子：
1.8
通讯作者：
Kang, HC
中科院分区：
文献类型：
--
作者：
Gee, KR;Archer, EA;Kang, HC
生物聚合物标记分子的4-磺基-2，3，5，6-四氟苯基（STP）酯显示出比相应的N-羟基琥珀酰亚胺基（NHS）酯显著更易溶于水。这些STP酯容易合成，并且容易与伯胺反应，得到与NHS和五氟苯基（PFP）酯相同的酰化产物。(C)1999爱思唯尔科技有限公司。保留所有权利。
4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) esters of biopolymer-labeling molecules are shown to be dramatically more water-soluble than the corresponding N-hydroxysuccinimidyl (NHS) esters. These STP esters are easily synthesized, and react readily with primary amines to give the same acylation products as NHS and pentafluorophenyl (PFP) esters. (C) 1999 Elsevier Science Ltd. All rights reserved.