Preliminary development of the World Health Organsiation's Quality of Life HIV instrument (WHOQOL-HIV): analysis of the pilot version
Preliminary development of the World Health Organsiation's Quality of Life HIV instrument (WHOQOL-HIV): analysis of the pilot version
复制标题
DOI：
10.1016/s0277-9536(02)00506-3
复制
发表时间：
2003-10-01
影响因子：
5.4
通讯作者：
Saxena, S
中科院分区：
文献类型：
--
作者：
O'Connell, K;Skevington, S;Saxena, S
生活质量（QoL）评估对于了解艾滋病毒感染如何影响人们的生活至关重要。为跨文化使用而开发的可靠和有效的衡量工具对于评价该疾病的全球影响将是重要的。本文报告了WHOQOL-HIV试点工具的开发和初步评估，该工具旨在与WHOQOL-100一起用于艾滋病毒感染者和艾滋病患者（PLWHA）。在这项研究中，来自六个文化多样性地区的900名平均年龄为32岁的人完成了WHOQOL-100沿着115项艾滋病毒特异性项目。应答者是艾滋病毒无症状者（23%）、艾滋病毒有症状者（23%）、艾滋病患者（20%）或健康者（34%）。通过分析，从试点工具中选择最佳项目，结果纳入了33个项目，涵盖12个新的方面，用于世卫组织生活质量-艾滋病毒工具的现场试验版本;例如艾滋病毒症状，身体形象，社会包容，死亡和垂死，以及宽恕。结果表明，该量表（α = 0.98）及其领域（α = 0.87-0.94）具有良好的内部一致性。对于艾滋病毒感染者和艾滋病患者，疼痛和不适，积极的感觉，对药物的依赖，性活动，财政资源和精神联系特别差，这表明艾滋病毒最严重的影响超出了身体健康，延伸到生活质量的心理-社会-精神和环境领域。使用ANOVA进行的比较显示，处于HIV感染后期或目前患病的人报告的生活质量比健康的人差（p
The assessment of quality of life (QoL) is central to understanding how people's lives are affected by HIV infection. A reliable and valid measurement tool developed for cross-cultural use will be important in evaluating the global impact of the disease. This paper reports on the development and preliminary assessment of the WHOQOL-HIV pilot instrument that is designed for use with the WHOQOL-100 for persons living with HIV and AIDS (PLWHA). In this study, 900 people with a mean age of 32 from six culturally diverse sites completed the WHOQOL-100 along with 115 HIV specific items. Respondents were HIV asymptomatic (23%), HIV symptomatic (23%), had AIDS (20%) or were well (34%). Analyses to select the best items from the piloted instrument resulted in the inclusion of 33 items covering 12 new facets for a field trial version of the WHOQOL-HIV instrument; e.g. symptoms of HIV, body image, social inclusion, death and dying, and forgiveness. The results indicate excellent internal consistency for the scale (alpha = 0.98) and its domains (alpha = 0.87-0.94). For PLWHA, pain and discomfort, positive feelings, dependence on medication, sexual activity, financial resources and spiritual connection were particularly poor, indicating that the severest impact of HIV extends beyond physical well-being to the psycho-social-spiritual and environmental areas of QoL. Comparisons using ANOVA showed that persons who are at later stages of HIV infection, or are currently ill report poorer QoL than those that were well (p