Rehabilitation with dental prosthesis can increase cerebral regional blood volume
Rehabilitation with dental prosthesis can increase cerebral regional blood volume
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DOI：
10.1111/j.1600-0501.2005.01171.x
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发表时间：
2005-12-01
影响因子：
4.3
通讯作者：
Iizuka, T
中科院分区：
文献类型：
--
作者：
Miyamoto, I;Yoshida, K;Iizuka, T
无牙颌患者的义齿治疗对于维持生活质量是非常重要的。然而，它对大脑的影响尚不清楚。在这项实验研究中，我们假设牙科修复体不仅可以恢复咀嚼系统的物理状态，而且可以恢复局部的脑活动。我们用多通道近红外光学地形图评价了牙种植体修复体固定咬合任务的无牙颌受试者的脑功能成像。结果显示(P<；0.001；配对t检验)在种植体固位的最大自愿咬合任务中，大脑区域血容量显著增加。戴假体和不戴假体的患者在任务完成后达到最大区域血容量的潜伏期无统计学差异。综上所述，咬合可以有效地增加脑血容量；因此，保持正常的咀嚼可能会防止大脑退化。
Treatment with denture for edentulous people is highly important for maintaining quality of life. However, its effect on the brain is unknown. In this experimental study, we hypothesized that dental prosthesis can recover not only the physical condition of mastication system but also the regional brain activity. We evaluated functional brain imaging of edentulous subjects fixed by dental implant prosthesis with clenching tasks by multi-channel near-infrared optical topography. Results revealed a significantly (P < 0.001; paired t-test) increased cerebral regional blood volume during maximum voluntary clenching task by implant-retained prosthesis. There were no statistically significant differences between patients with and without prosthesis in the latency to the maximum regional blood volume after the task. Conclusively, clenching can be effective for increasing cerebral blood volume; accordingly maintenance of normal chewing might prevent the brain from degenerating.