Oxidative stress tolerance and longevity in Arabidopsis:: the late-flowering mutant gigantea is tolerant to paraquat
Oxidative stress tolerance and longevity in Arabidopsis:: the late-flowering mutant gigantea is tolerant to paraquat
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DOI：
10.1046/j.1365-313x.1998.00168.x
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发表时间：
1998-06-01
期刊：
影响因子：
7.2
通讯作者：
Inzé, D
中科院分区：
文献类型：
--
作者：
Kurepa, J;Smalle, J;Inzé, D
最近对动物寿命的遗传分析表明，长寿的品种对环境压力的耐受性更强。为了研究拟南芥的长寿是否也与胁迫耐受性的增加相关，测试了11个晚花突变体对产生超氧自由基的除草剂百草枯的反应。当植物暴露于低剂量的除草剂时，发现开花时间和百草枯耐受性之间存在紧密的相关性。此外，开花时间延迟最长的突变体（gi-3）对百草枯诱导的氧化胁迫具有较高的耐受水平。与野生型相比，所有测试的gi等位基因对百草枯毒性的耐受性增加，尽管实际耐受性水平不同。此外，gi-3突变体对过氧化氢的耐受性更强。这些结果表明，植物寿命和抗氧化应激能力之间的联系与动物相似，这意味着这种现象可能普遍存在于所有需氧生物体中。
Recent genetic analyses of longevity in animals have revealed that long-lived strains are more tolerant to environmental stresses. To investigate whether extended longevity in Arabidopsis also correlates with an increase in stress tolerance, the response was tested of 11 late-flowering mutants to the superoxide radical-generating herbicide paraquat. A tight correlation between flowering time and paraquat tolerance was found when plants were exposed to low doses of herbicide. Furthermore, the mutant gigantea (gi-3) with the longest delay in flowering time had a high tolerance level to paraquat-induced oxidative stress. All the tested gi alleles had an increased tolerance to paraquat toxicity compared to wild-type, although the actual levels of tolerance differed. In addition, the gi-3 mutant was more tolerant to hydrogen peroxide. These results suggest that the link between longevity and oxidative stress resistance in plants is similar to that found in animals, implying that this phenomenon may be general for all aerobic organisms.