Blood lactoferrin release induced by running exercise in normal volunteers: antibacterial activity

Blood lactoferrin release induced by running exercise in normal volunteers: antibacterial activity
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DOI:
10.1016/j.cccn.2003.12.001
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发表时间:
2004-03-01
影响因子:
5
通讯作者:
Kaibara, K
Kaibara, K
中科院分区:
医学3区
文献类型:
--
作者:
Inoue, H;Sakai, M;Kaibara, K

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被引文献

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背景资料:本研究的目的是测定跑步运动前后血清乳铁蛋白浓度和血清抗菌活性。研究方法:24名健康年轻男性被随机分为高、中、低强度运动组(分别以180、130和80步/分的速度跑5000步)。分别于运动前、运动后即刻、运动后1 h和运动后4 h采集血样。测定循环中性粒细胞、血清乳铁蛋白、全血铁和血清铁的浓度。用活的藤黄微球菌评价血清的抗菌活性。结果:运动后1h,高、中剂量组外周血中性粒细胞数分别增加20.0%和15.5%(P
Background: The aim of this study was to determine serum lactoferrin concentrations and serum antibacterial activity before and after running exercise. Methods: Twenty-four healthy young men were randomly assigned to high, middle, or low intensity of exercise groups (5000 steps running at 180, 130, and 80 steps/min, respectively). Blood samples were collected at baseline and immediately, I and 4 h after exercise. Concentrations of circulating neutrophils, serum lactoferrin, iron in whole blood, and serum iron were measured. Antibacterial activity of serum was evaluated using live Micrococcus luteus. Results: The numbers of circulating neutrophils were increased by 20.0% and 15.5% 1 h after exercise in high and middle groups (both P