STRUCTURE OF EVOLVING POPULATIONS OF SACCHAROMYCES-CEREVISIAE - ADAPTIVE-CHANGES ARE FREQUENTLY ASSOCIATED WITH SEQUENCE ALTERATIONS INVOLVING MOBILE ELEMENTS BELONGING TO THE TY FAMILY
STRUCTURE OF EVOLVING POPULATIONS OF SACCHAROMYCES-CEREVISIAE - ADAPTIVE-CHANGES ARE FREQUENTLY ASSOCIATED WITH SEQUENCE ALTERATIONS INVOLVING MOBILE ELEMENTS BELONGING TO THE TY FAMILY
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DOI：
10.1073/pnas.83.18.7124
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发表时间：
1986-09-01
影响因子：
11.1
通讯作者：
OELLER, PW
中科院分区：
文献类型：
--
作者：
ADAMS, J;OELLER, PW
单倍体a和二倍体a/α。和在实验室环境中进化达300代的酿酒酵母的a/a群体分析与转座因子的Ty家族相关的序列重排。与大肠杆菌的结果相反，不断进化的酵母菌群体表现出与移动的遗传元件相关的高频率的序列重排。特别是，在这些人群中的适应性变化往往与这种序列重排。结果是最兼容的解释，有直接选择的一些序列重排。此外，变化模式表明，不断演变的微生物种群的结构可能比预期的更复杂。
Haploid a and diploid a/.alpha. and a/a populations of Saccharomyces cerevisiae evolving in laboratory environments for up to 300 generations were analyzed for sequence rearrangements associated with the Ty family of transposable elements. In contrast to results with Escherichia coli, evolving populations of yeast exhibit a high frequency of sequence rearrangements associated with mobile genetic elements. In particular, adaptive shifts in these populations are often associated with such sequence rearrangements. The results are most compatible with the explanation that there is direct selection for some of the sequence rearrangements. In addition, the pattern of changes suggests that the structure of evolving microorganism populations may be more complex than expected.