Language lateralization in a bimanual language
Language lateralization in a bimanual language
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DOI：
10.1162/jocn.2003.15.5.718
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发表时间：
2003-07-01
影响因子：
3.2
通讯作者：
Braun, AR
中科院分区：
文献类型：
--
作者：
Corina, DP;Jose-Robertson, LS;Braun, AR
与口语不同，聋人的标志性语言利用两个主要的表达式（左手和左手）来产生标志，这种情况在口语中没有明显的相似之处，在这种语言中，在这种情况下，由对称的单一中线人声结构进行了语音表达。这种安排提供了一个独特的机会，可以检查语言系统的鲁棒性，这些语言系统面对对比的发音需求，并绘制了惯用性运动对高科技运动的差异效果。正电子发射断层扫描（PET）技术用于检查16种美国手语（ASL）聋哑使用者的大脑激活，而受试者则独立地产生动词标志，并以其右主导和左手非主导手（与名词标志的重复相比），几乎相同观察到左下额叶和右小脑活性的模式。签名期间的这种激活模式与已经报道的口头语言的模式一致，包括有关与词汇语义处理，搜索和检索以及语音编码相关的较低额叶区域的证据。这些结果表明，生产中的词汇语义处理依赖于左半球区域，无论其实现语言的方式如何，而且即使面对矛盾的表达要求，这种左半球激活也是稳定的。此外，这些数据还提供了右后外侧小脑在语言认知处理中的作用的证据，以及左侧腹梭形对手语处理的贡献的证据。
Unlike spoken languages, sign languages of the deaf make use of two primary articulators, the right and left hands, to produce signs, This situation has no obvious parallel in spoken languages, in which speech articulation is carried out by symmetrical unitary midline vocal structures. This arrangement affords a unique opportunity to examine the robustness of linguistic systems that underlie language production in the face of contrasting articulatory demands and to chart the differential effects of handedness for highly skilled movements. Positron emission tomography (PET) technique was used to examine brain activation in 16 deaf users of American Sign Language (ASL) while subjects generated verb signs independently with their right dominant and left nondominant hands (compared to the repetition of noun signs), Nearly identical patterns of left inferior frontal and right cerebellum activity were observed. This pattern of activation during signing is consistent with patterns that have been reported for spoken languages including evidence for specializations of inferior frontal regions related to lexical-semantic processing, search and retrieval, and phonological encoding. These results indicate that lexical-semantic processing in production relies upon left-hemisphere regions regardless of the modality in which a language is realized, and that this left-hemisphere activation is stable, even in the face of conflicting articulatory demands. in addition, these data provide evidence for the role of the right posterolateral cerebellum in linguistic-cognitive processing and evidence of a left ventral fusiform contribution to sign language processing.