Changes in symptoms during urologic chronic pelvic pain syndrome symptom flares: findings from one site of the MAPP Research Network.
Changes in symptoms during urologic chronic pelvic pain syndrome symptom flares: findings from one site of the MAPP Research Network.
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泌尿科慢性盆腔疼痛综合征症状发作期间症状的变化：来自 MAPP 研究网络一个站点的发现。
DOI：
10.1002/nau.22534
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发表时间：
2015
影响因子：
2
通讯作者：
Lai,HHenry
中科院分区：
文献类型：
--
作者：
Sutcliffe,Siobhan;Colditz,GrahamA;Pakpahan,Ratna;Bradley,CatherineS;Goodman,MelodyS;Andriole,GeraldL;Lai,HHenry
目的首次描述和量化间质性膀胱炎/膀胱疼痛综合征和慢性前列腺炎/慢性盆腔疼痛综合征症状加重期间的症状变化方法慢性盆腔疼痛流行病学和表型研究的跨学科方法的一个研究中心的参与者在1年的研究随访期间完成了两个10天的日记，一个在基线，一个在他们的第一次爆发期间（如果不在基线）。在日记的每一天，参与者报告他们目前是否正在经历发作，定义为至少1天的“比平常严重得多的症状”，以及他们的排尿相关疼痛，骨盆疼痛，尿急和频率水平（0-10分）。线性混合模型被用来计算平均变化的症状之间的非耀斑和耀斑天从同一participator.Results27名妇女和9 29名男子在随访期间至少有一个耀斑，共281非耀斑和210耀斑天。在这些参与者中，在20天的合并日志观察期内，44.4%报告了1次发作，29.6%报告了2次发作，25.9%报告了≥3次发作，报告的发作持续时间从1天到>2周不等。在这些突发事件中，每个主要症状明显恶化，平均至少两个点，总症状恶化，平均11点，男女（所有P ≤ 0.01）。Urodynam。34：188-195，2015.© 2013 Wiley Periodicals，Inc.
AimsTo provide the first description and quantification of symptom changes during interstitial cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome symptom exacerbations (“flares”).MethodsParticipants at one site of the Trans‐Multidisciplinary Approaches to the study of chronic Pelvic Pain Epidemiology and Phenotyping Study completed two 10‐day diaries over the 1‐year study follow‐up period, one at baseline and one during their first flare (if not at baseline). On each day of the diary, participants reported whether they were currently experiencing a flare, defined as “symptoms that are much worse than usual” for at least 1 day, and their levels of urination‐related pain, pelvic pain, urgency, and frequency on a scale of 0–10. Linear mixed models were used to calculate mean changes in symptoms between non‐flare and flare days from the same participant.ResultsEighteen of 27 women and 9 of 29 men reported at least one flare during follow‐up, for a total of 281 non‐flare and 210 flare days. Of these participants, 44.4% reported one flare, 29.6% reported two flares, and 25.9% reported ≥3 flares over the combined 20‐day diary observation period, with reported flares ranging in duration from 1 day to >2 weeks. During these flares, each of the main symptoms worsened significantly by a mean of at least two points and total symptoms worsened by a mean of 11 points for both sexes (allP≤ 0.01).ConclusionsFlares are common and correspond to a global worsening of urologic and pelvic pain symptoms.Neurourol. Urodynam. 34:188–195, 2015. © 2013 Wiley Periodicals, Inc.