Nano-Fluidic Millimeter-Wave Lab-on-a-Waveguide Sensor for Liquid-Mixture Characterization
Nano-Fluidic Millimeter-Wave Lab-on-a-Waveguide Sensor for Liquid-Mixture Characterization
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DOI：
10.1109/jsen.2017.2772348
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发表时间：
2018-01-01
影响因子：
4.3
通讯作者：
Somjit, Nutapong
中科院分区：
文献类型：
--
作者：
Chudpooti, Nonchanutt;Silavwe, Evans;Somjit, Nutapong
本文报道了一种小型化的实验室上的波导液体混合物传感器，实现高度准确的纳升液体样品表征，生物医学应用。纳米流体集成毫米波传感器的设计是基于近场传输线技术，实现了一个单一的环路缝隙天线工作在91 GHz，制作成一个基于光激光器的减材制造WR-10矩形波导的盖子。安装在天线孔径顶部的纳米流体子系统通过使用多个聚四氟乙烯层来制造，以在实验期间封装和隔离液体样品，因此，提供各种优选的特征，例如，非侵入式和非接触式测量。此外，该传感器可通过仅替换纳米流体子系统来重复使用，从而产生具有成本效益的传感器。该新型传感器可以测量低至210纳升的液体体积，同时仍然实现乙醇/去离子水液体混合物中乙醇的优于2%的区分准确度，其中至少三次重复测量的标准偏差低于0.008，导致迄今为止报道的最高准确度的乙醇和去离子水混合物。纳米流体集成的毫米波传感器还提供了其他优点，如易于设计，制造和材料成本低，没有毫米波子系统的生命周期限制。
This paper reports on a miniaturized lab-on-a-waveguide liquid-mixture sensor, achieving highly accurate nano-liter liquid sample characterization, for biomedical applications. The nanofluidic-integrated millimeter-wave sensor design is based on a near-field transmission-line technique implemented by a single loop slot antenna operating at 91 GHz, fabricated into the lid of a photolaser-based subtractive manufactured WR-10 rectangular waveguide. The nanofluidic subsystem, which is mounted on the top of the antenna aperture, is fabricated by using multiple polytetrafluoroethylene layers to encapsulate and isolate the liquid sample during the experiment, hence, offering various preferable features, e.g., noninvasive and contactless measurements. Moreover, the sensor is reusable by replacing only the nanofluidic subsystem, resulting in a cost-effective sensor. The novel sensor can measure a liquid volume of as low as 210 nano-liters, while still achieving a discrimination accuracy of better than 2% of ethanol in the ethanol/deionized-water liquid mixture with a standard deviation of lower than 0.008 from at least three repeated measurements, resulting in the highest accurate ethanol and DI-water discriminator reported to date. The nanofluidic-integrated millimeter-wave sensor also offers other advantages, such as the ease of design, low fabrication and material cost, and no life-cycle limitation of the millimeter-wave subsystem.