Metabolites from the endophytic fungus Phomopsis sp PSU-D15
Metabolites from the endophytic fungus Phomopsis sp PSU-D15
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DOI：
10.1016/j.phytochem.2007.09.006
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发表时间：
2008-02-01
期刊：
影响因子：
3.8
通讯作者：
Kirtikara, Kanyawim
中科院分区：
文献类型：
--
作者：
Rukachaisirikul, Vatcharin;Sommart, Ubonta;Kirtikara, Kanyawim
从内生真菌拟茎点霉（Phomopsis sp.）PSU-D 15中分离得到3个代谢产物，分别命名为phomoenamide（1）、phomonitroester（2）和deacetylphomoxanthone B（3），另外还分离得到3个已知化合物，分别命名为dicerandrol A（4）、（1 S，2S，4S）-p-mentane-1，2，4-triol（5）和尿苷。用波谱方法鉴定了它们的结构。Phomoenamide（1）对结核分枝杆菌H37 Ra表现出中等的体外抗分枝杆菌活性。(c)2007爱思唯尔有限公司保留所有权利。
From the endophytic fungus Phomopsis sp. PSU-D15, three metabolites named as phomoenamide (1), phomonitroester (2) and deacetylphomoxanthone B (3), were isolated together with three known compounds, dicerandrol A (4), (1S,2S,4S)-p-menthane-1,2,4-triol (5) and uridine. Their structures Were elucidated by spectroscopic methods. Phomoenamide (1) exhibited moderate in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Ra. (c) 2007 Elsevier Ltd. All rights reserved.