Traveling young injection drug users at high risk for acquisition and transmission of viral infections
Traveling young injection drug users at high risk for acquisition and transmission of viral infections
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DOI：
10.1016/j.drugalcdep.2007.08.016
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发表时间：
2008-01-11
影响因子：
4.2
通讯作者：
Lum, Paula J.
中科院分区：
文献类型：
--
作者：
Hahn, Judith A.;Page-Shafer, Kimberly;Lum, Paula J.
背景：青少年注射吸毒者(IDU)流动性强。目前尚不清楚流动性如何影响他们感染和传播病毒感染的风险。方法：我们对旧金山的青少年(30岁以下)进行了一项横断面研究(2004-2006)。参与者完成了对乙肝病毒(乙肝病毒)、丙型肝炎病毒(丙型肝炎病毒)和艾滋病毒感染的半结构化面试和测试。在调整了人口统计学特征和注射年限后，我们检查了旅行是否与药物、酒精、性危险行为和感染状况独立相关。结果：三分之二(62%)的人报告过去(3个月)去过旧金山以外的地方(n=355)。与非旅行者相比，旅行者更有可能在20岁以下，女性，并计划在未来几个月离开旧金山。旅行与大量饮酒、在昏迷前饮酒、使用多种物质、更多的性伴侣和注射伴侣、接受针头/注射器共用、共用药物制备设备、给注射器装填后备药和集资购买毒品独立相关。在与旅行的互动分析中，年轻的旅行者比年轻的非旅行者更有可能感染丙型肝炎病毒。讨论：旅行的年轻注射吸毒者感染和传播病毒的风险非常高，而他们的流动性使有效提供干预措施具有挑战性。(C)2007爱思唯尔爱尔兰有限公司。保留所有权利。
Background: Young injection drug users (IDU) are highly mobile. It is not known how mobility affects their risk of acquiring and transmitting viral infections.Methods: We conducted a cross-sectional study of young (under age 30) IDU in San Francisco (2004-2006). Participants completed a semistructured interview and testing for hepatitis B virus (HBV), hepatitis C virus (HCV) and HIV infection. We examined whether travel was independently associated with drug, alcohol, sexual risk behaviors, and infection status, after adjusting for demographic characteristics and years injecting.Results: Two-thirds (62%) reported past (3 months) travel outside of San Francisco (n= 355). Travelers, as compared to non-travelers, were more likely to be under age 20, female, and planned to leave San Francisco in the coming months. Travel was independently associated with heavy alcohol consumption, drinking alcohol until blackout, poly-substance use, more sexual and injecting partners, and receptive needle/syringe sharing, sharing drug preparation equipment, backloading syringes and pooling money to buy drugs. In an analysis of interactions with travel, younger travelers were more likely to be HCV positive than younger non-travelers.Discussion: Traveling young IDU are at exceptionally high risk for acquiring and transmitting viral infections, while their mobility makes it challenging to effectively deliver interventions. (c) 2007 Elsevier Ireland Ltd. All rights reserved.