OXIDATION OF GLUTATHIONE BY HYDROGEN-PEROXIDE AND OTHER OXIDIZING-AGENTS
OXIDATION OF GLUTATHIONE BY HYDROGEN-PEROXIDE AND OTHER OXIDIZING-AGENTS
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DOI：
10.1021/jf00104a045
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发表时间：
1981-01-01
影响因子：
6.1
通讯作者：
WITT, SC
中科院分区：
文献类型：
--
作者：
FINLEY, JW;WHEELER, EL;WITT, SC
用过氧化氢、过氧化苯甲酰、溴酸钾和亚油酸氢过氧化物氧化还原型谷胱甘肽（GSH）。通过氨基酸分析或通过1H NMR测量所得氧化化合物。在不同pH值下氧化谷氨酸，并测量氧化产物的比率。酸水解和氨基酸分析后观察到的各种水解产物进行了讨论，并与完整的谷胱甘肽上的1H NMR的结果。
Reduced glutathione (GSH) in aqueous solution was oxidized with hydrogen peroxide, benzoyl peroxide, potassium bromate and linoleic acid hydroperoxide. The resulting oxidized compounds were measured by amino acid analysis or by 1H NMR. Glutathione was oxidized at various pH values and the ratios of the oxidation products were measured. The various hydrolysis products observed after acid hydrolysis and amino acid analysis are discussed and related to the results with 1H NMR on intact glutathione.