Sleep apnea and nocturnal myoclonus in a senior population.
Sleep apnea and nocturnal myoclonus in a senior population.
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老年人群中的睡眠呼吸暂停和夜间肌阵挛。
作者：
Ancoli-Israel,S;Kripke,DF;Mason,W;Messin,S
研究表明，睡眠呼吸暂停在老年人中尤其普遍，我们招募并记录了老年志愿者，他们报告了怀疑睡眠呼吸暂停或夜间肌阵挛的症状。在24名受试者中，62.5%的人患有其中一种疾病，其中6人仅患有睡眠呼吸暂停，3人患有睡眠呼吸暂停和夜间肌阵挛，6人仅患有夜间肌阵挛。睡眠阶段也进行了分析。与其他受试者相比，睡眠呼吸暂停和/或夜间肌阵挛受试者的快速眼动睡眠显著减少，第1阶段睡眠显著增加，觉醒显著增加。这一样本表明，睡眠呼吸暂停和夜间肌阵挛的患病率可能是非常可观的老年人。由于这种高患病率，在为有睡眠投诉的老年患者开催眠药时需要极其谨慎，因为大多数催眠药都是呼吸抑制药。我们必须重新思考我们治疗老年人睡眠障碍的方法。
Studies have suggested that sleep apnea is especially prevalent among seniors, We recruited and recorded senior volunteers who reported symptoms raising suspicion of sleep apnea or nocturnal myoclonus. Of 24 subjects, 62.5% had one of these disorders—six had sleep apnea alone, three had sleep apnea and nocturnal myoclonus, and six had nocturnal myoclonus alone. Sleep stages were also analyzed. Subjects with sleep apnea and/or nocturnal myoclonus had significantly less rapid eye movement sleep, significantly more stage 1 sleep, and significantly more awakenings than other subjects. This sample suggests that the prevalence of sleep apnea and nocturnal myoclonus may be very substantial among seniors. Because of this high prevalence, extreme caution is needed in prescribing hypnotics for older patients with sleep complaints, since most hypnotics are respiratory depressants. We must rethink our approach to treating sleep disorders in the older population.