Shear Wave Elastography for Evaluation of Liver Fibrosis
Shear Wave Elastography for Evaluation of Liver Fibrosis
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DOI：
10.7863/ultra.33.2.197
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发表时间：
2014-02-01
影响因子：
2.3
通讯作者：
Filice, Carlo
中科院分区：
文献类型：
--
作者：
Ferraioli, Giovanna;Parekh, Parth;Filice, Carlo
慢性病毒性肝炎的预后和治疗主要取决于肝纤维化的程度，特别是慢性丙型肝炎。肝组织学分析仍然被认为是评估肝纤维化的参考标准，尽管在分期和一些发病率和死亡率风险的观察者和观察者之间的变异性。因此，用于评估肝纤维化的非侵入性方法具有很大的临床意义。在过去的十年中，基于超声的技术来估计肝纤维化的阶段已经成为商业可用。它们都具有通过测量施加机械应力时的组织行为来非侵入性地评估软组织弹性特性差异的能力。剪切波弹性成像依赖于剪切波的产生，所述剪切波由聚焦超声波束的力或外部推力引起的组织位移确定。本文综述了剪切波弹性成像评估肝纤维化的结果。
The prognosis and management of chronic viral hepatitis mainly depend on the extent of liver fibrosis, particularly in chronic hepatitis C. Liver histologic analysis is still considered the reference standard in the assessment of liver fibrosis despite the interobserver and interobserver variability in staging and some morbidity and mortality risks. Thus, noninvasive methods for assessing liver fibrosis are of great clinical interest. In the last decade, ultrasound-based techniques to estimate the stage of liver fibrosis have become commercially available. They all have the capability to noninvasively evaluate differences in the elastic properties of soft tissues by measuring tissue behavior when a mechanical stress is applied. Shear wave elastography relies on the generation of shear waves determined by the displacement of tissues induced by the force of a focused ultrasound beam or by an external push. This article reviews the results that have been obtained with shear wave elastography for assessment of liver fibrosis.