Bilateral, isolated, lateral semicircular canal malformation without hearing loss
Bilateral, isolated, lateral semicircular canal malformation without hearing loss
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双侧孤立性侧半规管畸形，无听力损失
DOI：
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发表时间：
2008
影响因子：
1.7
通讯作者：
A. Casani
中科院分区：
文献类型：
--
作者：
I. Dallan;S. Berrettini;E. Neri;A. Casani
摘要假设：内耳畸形是常见于感音神经性听力损失患者。然而，内耳前庭部分的孤立异常很少被描述，因此它们对平衡的影响也知之甚少。护理报告：我们提出的情况下，38岁的白人男子与经常前庭投诉，与线性倾斜的感觉，但没有听力障碍。临床和神经耳科检查显示前庭系统的外周受累，而听力学调查在正常范围内。高分辨率磁共振成像的内耳，三维重建，表现出孤立的前庭异常，涉及外半规管和椭圆囊。结论：考虑到这种情况下，我们推测，孤立的前庭畸形可能并不像以前认为的那样罕见，应该调查与先进的成像技术的帮助。综述了相关文献，集中注意力在分子方面，也报道。
Abstract Hypothesis: Inner-ear malformations are frequently found in patients with sensorineural hearing loss. However, isolated anomalies of the vestibular part of the inner ear are seldom described, and for this reason their impact on balance is poorly understood. Care report: We present the case of a 38-year-old Caucasian man with recurrent vestibular complaints, with a sensation of linear tilting, but no hearing impairment. Clinical and neuro-otological examinations showed peripheral involvement of the vestibular system, while audiological investigation was within normal limits. High-resolution magnetic resonance imaging of the inner ear, with three-dimensional reconstruction, demonstrated isolated vestibular anomalies involving both the lateral semicircular canal and the utricle. Conclusions: Bearing in mind this case, we speculate that isolated vestibular malformation may not be as rare as previously thought, and should be investigated with the aid of sophisticated imaging techniques. A review of the relative literature, focussing attention on the molecular aspects, is also reported.
影响因子：
4.6
作者：
H. Morsli;F. Tuorto;Daniel I. Choo;M. Postiglione;Antonio Simeone;Doris K. Wu
通讯作者：
H. Morsli;F. Tuorto;Daniel I. Choo;M. Postiglione;Antonio Simeone;Doris K. Wu