Effect of Miracidial Dose on Adoptively Transferred Resistance to Schistosoma mansoni in the Snail Intermediate Host, Biomphalaria glabrata
Effect of Miracidial Dose on Adoptively Transferred Resistance to Schistosoma mansoni in the Snail Intermediate Host, Biomphalaria glabrata
复制标题
毛霉剂量对蜗牛中间宿主光滑双脐螺过继转移抗性曼氏血吸虫的影响
作者:
René E. Vasquez;J. Sullivan
Adoptively transferred resistance to Schistosoma mansoni in the snail intermediate host Biomphalaria glabrata was measured as a function of miracidial challenge dose. Schistosome-susceptible snails implanted with the amebocyte-producing organ (APO) from resistant donors showed 29 and 39% prevalences of infection after challenge with 5 and 10 miracidia, respectively, but 68–83% prevalences when exposed to 25–200 miracidia. Prevalences in control (untampered) susceptible snails ranged from 97 to 100% at the different miracidial doses. Higher infection prevalences at elevated doses suggest that a range of transferred resistance occurs and possibly that low levels of APO-derived plasma factors or hemocytes in some recipients can be overwhelmed by larger numbers of parasites.
影响因子:
2.1
作者:
GranathJr,WO;Yoshino,TP
通讯作者:
Yoshino,TP
DOI:
--
发表时间:
1999
期刊:
The Journal of parasitology.
影响因子:
--
作者:
Sullivan,JT;Spence,JV
通讯作者:
Spence,JV