Effect of Miracidial Dose on Adoptively Transferred Resistance to Schistosoma mansoni in the Snail Intermediate Host, Biomphalaria glabrata

Effect of Miracidial Dose on Adoptively Transferred Resistance to Schistosoma mansoni in the Snail Intermediate Host, Biomphalaria glabrata
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毛霉剂量对蜗牛中间宿主光滑双脐螺过继转移抗性曼氏血吸虫的影响

DOI:
--
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发表时间:
2001
影响因子:
1.3
通讯作者:
J. Sullivan
J. Sullivan
中科院分区:
医学4区
文献类型:
--
作者:
René E. Vasquez;J. Sullivan

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Adoptively transferred resistance to Schistosoma mansoni in the snail intermediate host Biomphalaria glabrata was measured as a function of miracidial challenge dose. Schistosome-susceptible snails implanted with the amebocyte-producing organ (APO) from resistant donors showed 29 and 39% prevalences of infection after challenge with 5 and 10 miracidia, respectively, but 68–83% prevalences when exposed to 25–200 miracidia. Prevalences in control (untampered) susceptible snails ranged from 97 to 100% at the different miracidial doses. Higher infection prevalences at elevated doses suggest that a range of transferred resistance occurs and possibly that low levels of APO-derived plasma factors or hemocytes in some recipients can be overwhelmed by larger numbers of parasites.
曼氏血吸虫:通过媒介蜗牛(Biomphalaria glabrata)中的血清被动转移耐药性。
DOI: 10.1016/0014-4894(84)90034-1
发表时间: 1984
影响因子: 2.1
作者:
GranathJr,WO;Yoshino,TP
通讯作者: Yoshino,TP
影响蜗牛中间宿主光滑双脐螺对曼氏血吸虫抗性过继转移的因素。
DOI: --
发表时间: 1999
期刊: The Journal of parasitology.
影响因子: --
作者:
Sullivan,JT;Spence,JV
通讯作者: Spence,JV