A comparison of approaches to the statistical analysis of [15O]H2O PET cognitive activation studies.
A comparison of approaches to the statistical analysis of [15O]H2O PET cognitive activation studies.
复制标题
[15O]H2O PET 认知激活研究统计分析方法的比较。
DOI：
10.1176/jnp.7.2.155
复制
发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Hichwa,RD
中科院分区：
文献类型：
--
作者：
Arndt,S;Cizadlo,T;Andreasen,NC;Zeien,G;Harris,G;O'Leary,DS;Watkins,GL;Ponto,LL;Hichwa,RD
本研究比较了两种最广泛使用的统计技术，用于分析从[15O] H2O PET脑功能研究中获得的数据。采用弗里斯顿方法（SPM94）和沃斯利方法（蒙特利尔）对33名被试的单一数据集进行了研究，这些被试采用了一个旨在评估单词列表记忆的范式。这两种方法都没有表现出明显的不同或明显的可取之处，尽管偶尔的差异在一些实验中可能很重要。总的来说，这两种方法在识别长期记忆中活跃的大脑区域（额叶、顶叶、扣带和小脑）方面产生了相似的结果。讨论了这两种方法的基本假设，以及它们的优缺点。
This study compares two of the most widely used statistical techniques for analyzing data obtained from [15O] H2O PET studies of brain function. The Friston method (SPM94) and the Worsley (Montreal) method were applied to a single data set of 33 subjects who were studied in a paradigm designed to evaluate memory for word lists. Neither of these methods emerged as either strikingly different or strikingly preferable, although the occasional differences may be important in some experiments. In general, the two methods were found to produce similar results in identifying brain regions active during long-term memory: frontal, parietal, cingulate, and cerebellar. Underlying assumptions of the two methods, as well as their strengths and weaknesses, are discussed.