PLASMA HOMOCYSTEINE LEVELS AND MORTALITY IN PATIENTS WITH CORONARY ARTERY DISEASE
PLASMA HOMOCYSTEINE LEVELS AND MORTALITY IN PATIENTS WITH CORONARY ARTERY DISEASE
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DOI：
10.1056/nejm199711273372215
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
An;Rik;Ordrehaug;Elga;Efsum;tein;Mil;Ollset
中科院分区：
文献类型：
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作者：
An;Rik;Ordrehaug;Elga;Efsum;tein;Mil;Ollset
通过反向Kaplan-Meier方法计算时间。25在所有回归分析中，协变量由指示变量表示，以允许非线性剂量-反应关系。还采用广义加性Logistic回归估计了总同型半胱氨酸水平与死亡率之间的剂量-反应关系，26如在S-PLUS中实施的。用BMDP 27或S-PLUS 24软件进行统计分析。认为双侧P值低于0.05表明具有统计学显著性。
time was calculated by the reverse Kaplan–Meier method. 25 In all regression analyses, the covariates were represented by indicator variables to allow for nonlinear dose–response relations. The dose–response relation between the total homocysteine level and mortality was also estimated with generalized additive logistic re- gression, 26 as implemented in S-PLUS. This method generates a graphic representation of the relation between the total homocys- teine level and mortality on a logit scale, after adjustment for other covariates.The analyses were performed with BMDP 27 or S-PLUS 24 software. Two-sided P values below 0.05 were considered to indicate statistical significance.