The toxic effect of the antibiotic metronidazole on aquatic organisms
The toxic effect of the antibiotic metronidazole on aquatic organisms
复制标题
DOI：
10.1016/s0045-6535(97)00324-x
复制
发表时间：
1997-12-01
期刊：
影响因子：
8.8
通讯作者：
HallingSorensen, B
中科院分区：
文献类型：
--
作者：
Lanzky, PF;HallingSorensen, B
对淡水和海洋生物测试了甲硝唑的急性毒性。测试显示对小球藻属有影响。和羊月月藻。获得的结果包括 72 小时 EC10 分别为 2.03 mg/l 和 19.9 mg/l，72 小时 EC50 值分别为 12.5 mg/l 和 40.4 mg/l。没有观察到对 Acaria tonsa 或 Brachydanio rerio 的急性致死作用。该研究证明了甲硝唑潜在的生态毒性作用，表明需要进一步调查药用物质的环境暴露情况。 (C) 1997 爱思唯尔科学有限公司。
The acute toxicity of metronidazole was tested on freshwater and marine organisms. The tests showed effect on Chlorella sp. and Selenastrum capricornutum. 72-hr EC10 of 2.03 mg/l and 19.9 mg/l respectively and 72-hr EC50 values of 12.5 mg/l and 40.4 mg/l respectively were among the results obtained. No acute lethal effect was observed on Acartia tonsa or Brachydanio rerio. The study demonstrates the potential ecotoxic effect of metronidazole, suggesting the need for further investigations of the environmental exposure of medicinal substances. (C) 1997 Elsevier Science Ltd.