Prospective study establishing a management plan for impacted third molar in patients undergoing hematopoietic stem cell transplantation
Prospective study establishing a management plan for impacted third molar in patients undergoing hematopoietic stem cell transplantation
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DOI：
10.1016/j.tripleo.2010.09.006
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发表时间：
2011-02-01
期刊：
影响因子：
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通讯作者：
Bukawa, Hiroki
中科院分区：
文献类型：
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作者：
Yamagata, Kenji;Onizawa, Kojiro;Bukawa, Hiroki
Objective.虽然在造血干细胞移植（HSCT）前进行牙科治疗对于预防口腔来源的严重感染至关重要，但对于阻生第三磨牙（ITM）的最佳治疗方案尚不清楚。本研究旨在为ITM制定管理计划。84名HSCT治疗的候选人连续入组前瞻性试验。管理计划，这是基于证据和前瞻性的决定，是提取症状的ITMs和无症状的未经治疗，无论他们的影响位置。在35例患者中观察到87例ITMs。ITMs位于上颌骨25例，下颌骨28例。6例患者拔除7颗牙，无并发症发生。所有患者均接受了预定的HSCT治疗，无骨髓抑制患者发生牙源性感染。该ITM管理计划似乎适用于HSCT前患者。此外，有经验的牙科医生被认为是HSCT团队中必要和有价值的一部分。(Oral口腔外科医学口腔病理学口腔放射学Endod 2011;111：146-152）
Objective. Although dental treatment before hematopoietic stem cell transplantation (HSCT) is essential to prevent serious infections from oral sources, the best management plan for impacted third molar (ITM) is unclear.Study design. This study was planned to establish a management plan for ITM. Eighty-four candidates for HSCT therapy were consecutively enrolled in the prospective trial. The management plan, which was evidence based and prospectively decided, was to extract the symptomatic ITMs and to leave the asymptomatic ones untreated, regardless of their impacted position.Results. Eighty-seven ITMs were observed in 35 patients. The ITMs were in the maxilla of 25 patients and the mandible of 28 patients. Dental extraction of 7 teeth was performed in 6 patients without complications. All of the patients received the scheduled HSCT therapy and none experienced odontogenic infection while myelosuppressed.Conclusions. This management plan for ITM appears to be appropriate for pre-HSCT patients. Moreover, the experienced dental provider is suggested as a necessary and valuable part of the HSCT team. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111:146-152)