Prognosis of canine patients with nasal tumors according to modified clinical stages based on computed tomography: A retrospective study
Prognosis of canine patients with nasal tumors according to modified clinical stages based on computed tomography: A retrospective study
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DOI：
10.1292/jvms.70.207
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发表时间：
2008-03-01
影响因子：
1.2
通讯作者：
Sasaki, Nobuo
中科院分区：
文献类型：
--
作者：
Kondo, Yumi;Matsunaga, Satoru;Sasaki, Nobuo
为了评价基于计算机断层扫描（CT）成像的临床分期相对于基于X线摄影的世界卫生组织（WHO）分期系统对犬鼻肿瘤的疗效，进行了一项回顾性研究。这项研究使用了112只患有鼻肿瘤的狗;它们接受了X线摄影和CT检查，并经组织学证实患有鼻肿瘤。在112只犬中，85只（75.9%）被诊断为腺癌。然后根据每个分期系统分析它们的生存时间。超过70%的腺癌患者被归类为WHO III期。归类为WHO II期的患者往往比归类为WHO III期的患者生存时间更长。分类为WHO III期的犬进一步分为CT III期和IV期，CT III期患者的生存时间显著长于CT IV期患者。此外，在CT III期，接受手术和放疗联合治疗的患者的生存时间明显长于未接受任何治疗的患者。另一方面，不同的治疗方式在CT IV期犬的生存时间方面没有显示出显著差异。结果表明，WHO III期犬可能有不同程度的肿瘤进展，表明CT分期系统可能比WHO分期系统更准确。
To evaluate the efficacy of clinical staging based on computed tomography (CT) imaging over the World Health Organization (WHO) staging system based on radiography for nasal tumors in dogs, a retrospective study was conducted. This study used 112 dogs that had nasal tumors; they had undergone radiography and CT and had been histologically confirmed as having nasal tumors. Among 112 dogs, 85 (75.9%) were diagnosed as adenocarcinoma. Then they were analyzed for survival time according to each staging system. More than 70% of the patients with adenocarcinoma were classified as having WHO stage III. The patients classified under WHO stage II tended to survive longer than those classified under WHO stage III. Dogs classified under WHO stage III were further grouped into CT stages Ill and IV, and CT stage III patients had a significantly longer survival time than CT stage IV patients. In addition, patients treated with a combination of surgery and radiation had a significantly longer survival time than the patients who did not receive any treatment in CT stage III. On the other hand, different treatment modalities did not show a significant difference in the survival time of CT stage IV dogs. The results suggest that WHO stage Ill dogs may have various levels of tumor progression, indicating that the CT staging system may be more accurate than the WHO staging system.