A straightforward multiparametric quality control protocol for proton magnetic resonance spectroscopy: Validation and comparison of various 1.5 T and 3 T clinical scanner systems
A straightforward multiparametric quality control protocol for proton magnetic resonance spectroscopy: Validation and comparison of various 1.5 T and 3 T clinical scanner systems
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DOI：
10.1016/j.ejmp.2018.08.013
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发表时间：
2018-10-01
影响因子：
3.4
通讯作者：
Giannelli, Marco
中科院分区：
文献类型：
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作者：
Sghedoni, Roberto;Coniglio, Angela;Giannelli, Marco
目的：本研究的目的是提出和验证各种临床扫描仪系统的一个简单的多参数质量保证程序质子磁共振spectroscopy（MRS）.Methods：18个临床1.5 T和3 T扫描仪系统的MRS，从16个中心和3个不同的制造商，参加了这项研究。所有中心均采用标准球形水模。采集方案包括3组单（各向同性）体素（尺寸20 mm）PRESS采集，水信号未被抑制，采集体素位置在等中心点以及偏离中心，在大约2个月内重复4/5次。结果：3 T和1.5T扫描仪的水峰线宽（LW）[平均值（标准差）]分别为1.4（1.0）Hz和0.8（0.3）Hz。对于采集体素的不同空间位置，LW和AP的平均（标准差）（所有扫描仪）变异系数分别为43%（20%）和11%（11%）。1.5 T和3 T扫描仪的平均（标准差）体模T-2值分别为1145（50）ms和1010（95）ms。LW，AP和T2重复测量的平均值（标准差）（所有扫描仪）的变异系数分别为25%（20%），10%（14%）和5%（2%.Conclusions）：我们提出了一个简单的多参数和不耗时的质量控制协议MRS，它可以包括在常规和定期的质量保证程序。该方案已在相当大量的临床1.5 T和3 T扫描仪系统的多中心比较研究中得到验证并证明是可行的。
Purpose: The aim of this study was to propose and validate across various clinical scanner systems a straightforward multiparametric quality assurance procedure for proton magnetic resonance spectroscopy (MRS).Methods: Eighteen clinical 1.5 T and 3 T scanner systems for MRS, from 16 centres and 3 different manufacturers, were enrolled in the study. A standard spherical water phantom was employed by all centres. The acquisition protocol included 3 sets of single (isotropic) voxel (size 20 mm) PRESS acquisitions with unsuppressed water signal and acquisition voxel position at isocenter as well as off-center, repeated 4/5 times within approximately 2 months. Water peak linewidth (LW) and area under the water peak (AP) were estimated.Results: LW values [mean (standard deviation)] were 1.4 (1.0) Hz and 0.8 (0.3) Hz for 3 T and 1.5 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficient of variation of LW and AP for different spatial positions of acquisition voxel were 43% (20%) and 11% (11%), respectively. The mean (standard deviation) phantom T-2 values were 1145 (50) ms and 1010 (95) ms for 1.5 T and 3 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficients of variation for repeated measurements of LW, AP and T2 were 25% (20%), 10% (14%) and 5% (2%), respectively.Conclusions: We proposed a straightforward multiparametric and not time consuming quality control protocol for MRS, which can be included in routine and periodic quality assurance procedures. The protocol has been validated and proven to be feasible in a multicentre comparison study of a fairly large number of clinical 1.5 T and 3 T scanner systems.