Sparsity and Biomechanics Inspired Integration of Shape and Speckle Tracking for Cardiac Deformation Analysis.
Sparsity and Biomechanics Inspired Integration of Shape and Speckle Tracking for Cardiac Deformation Analysis.
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DOI：
10.1007/978-3-319-20309-6_7
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发表时间：
2015-06
期刊：
影响因子：
--
通讯作者：
Duncan, James S
中科院分区：
文献类型：
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作者：
Parajuli, Nripesh;Compas, Colin B;Lin, Ben A;Sampath, Smita;O'Donnell, Matthew;Sinusas, Albert J;Duncan, James S
心脏运动分析，特别是左心室（LV）的运动分析，可以提供有关心脏功能状态的宝贵信息。我们提出了一种基于形状跟踪和斑点跟踪相结合的位移计算方法来计算心肌的密集变形场。我们介绍了在我们的积分方法中引入稀疏性的l1正则化的使用和效果。我们还引入正则化，使密集场更符合心脏生物力学。最后，我们提出了时间相干在密集场中的必要性，并展示了一种实现方法。我们在六个开胸犬心脏的超声图像上测试了我们的方法。基线和后闭塞应变结果提出了一个动物，在那里我们能够检测到缺血区域的显著变化。六组应变结果也与标记磁共振（MR）数据获得的应变进行了比较。径向应变和周向应变的中位相关系数（含mr标记）分别为0.73和0.82。
Cardiac motion analysis, particularly of the left ventricle (LV), can provide valuable information regarding the functional state of the heart. We propose a strategy of combining shape tracking and speckle tracking based displacements to calculate the dense deformation field of the myocardium. We introduce the use and effects of l1 regularization, which induces sparsity, in our integration method. We also introduce regularization to make the dense fields more adhering to cardiac biomechanics. Finally, we motivate the necessity of temporal coherence in the dense fields and demonstrate a way of doing so. We test our method on ultrasound (US) images acquired from six open-chested canine hearts. Baseline and post-occlusion strain results are presented for an animal, where we were able to detect significant change in the ischemic region. Six sets of strain results were also compared to strains obtained from tagged magnetic resonance (MR) data. Median correlation (with MR-tagging) coefficients of 0.73 and 0.82 were obtained for radial and circumferential strains respectively.