Insights on pathogenesis of type 2 diabetes from MODY genetics.
Insights on pathogenesis of type 2 diabetes from MODY genetics.
复制标题
DOI：
10.1007/s11892-007-0022-6
复制
发表时间：
2007-04-01
影响因子：
4.2
通讯作者：
Frayling, Timothy M
中科院分区：
文献类型：
--
作者：
Weedon, Michael N;Frayling, Timothy M
Maturity-onset diabetes of the young (MODY) is a type of non-insulin-dependent diabetes mellitus caused by rare autosomal-dominant mutations. MODY genes play key biochemical roles in the pancreatic beta cell; therefore, common variants of MODY genes are excellent candidate genes for type 2 diabetes. We review recent studies that suggest that common MODY gene variation contributes modestly to the heritability of type 2 diabetes.
