Diurnal mood variation in major depressive disorder
Diurnal mood variation in major depressive disorder
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DOI：
10.1037/1528-3542.6.3.383
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发表时间：
2006-08-01
期刊：
影响因子：
4.2
通讯作者：
Nicolson, Nancy A.
中科院分区：
文献类型：
--
作者：
Peeters, Frenk;Berkhof, Johannes;Nicolson, Nancy A.
抑郁症扰乱情绪，但抑郁症的昼夜情绪节律的清晰图像尚未出现。本研究探讨了积极情感（PA）和消极情感（NA）的变化，这两个维度的情绪，产生健康个体的昼夜模式。采用经验抽样法，对47例抑郁症患者和39例健康人进行了6天以上的NA和PA重复测量。相对于健康的人，抑郁症患者表现出增加PA水平在一天中，后来的acrophase。与此相反，抑郁症患者的NA表现出更明显的昼夜节律，更多变的时刻比健康的人。抑郁症患者的动态情绪测量表明，积极和消极情绪存在明显的昼夜紊乱。
Depression disturbs mood, but a clear picture of diurnal mood rhythms in depression has yet to emerge. This study examined variations in positive affect (PA) and negative affect (NA), two dimensions of mood that generate diurnal patterns among healthy individuals. Repeated measurements of NA and PA in daily life were obtained over 6 days from 47 depressed outpatients and 39 healthy individuals using the Experience Sampling Method. Relative to healthy individuals, depressed individuals exhibited increasing PA levels during the day with a later acrophase. In contrast, depressed persons' NA exhibited a more pronounced diurnal rhythm and was more variable from moment to moment than healthy individuals'. Ambulatory mood measurements in depression suggest distinct diurnal disturbances of positive and negative affect.