The new definition of metabolic syndrome by the international diabetes federation is less likely to identify metabolically abnormal but non-obese individuals than the definition by the revised national cholesterol education program: The Korea NHANES Study
The new definition of metabolic syndrome by the international diabetes federation is less likely to identify metabolically abnormal but non-obese individuals than the definition by the revised national cholesterol education program: The Korea NHANES Study
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DOI：
10.1038/sj.ijo.0803442
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发表时间：
2007-03-01
影响因子：
4.9
通讯作者：
Oh, S. W.
中科院分区：
文献类型：
--
作者：
Yoon, Y. S.;Lee, E. S.;Oh, S. W.
目的：IDF和修订后的NCEP提出的代谢综合征（MS）的新定义引起了一些混乱，因为出现了符合修订后的NCEP但不符合IDF标准的患者。我们进行了这项研究，以比较这些标准的患病率，并探讨差异的特点cases.Research设计和方法：共7962人年龄X 20岁（3597名男性，4365名女性）谁参加了1998年韩国NHANES。结果：修订后的NCEP诊断MS的患病率（男性25.7%、女性31.9%）高于IDF诊断MS的患病率（男性14.2%、女性26.6%）。根据修订后的NCEP标准，IDF标准未能确定44.9%的男性和16.6%的女性患有MS。与IDF和修订的NCEP标准的MS患者相比，尽管腰围较低，但差异组显示出更不利的代谢特征和不利的生活方式。不一致的情况下，患病率较高，在老年人。结论：IDF标准是劣于修订后的NCEP标准，在确定代谢异常，但非肥胖组已知易患2型糖尿病和心血管疾病。进一步研究的适当性，中心性肥胖作为一个强制性的标准提出的以色列国防军似乎是必要的。
Objective: The new definitions for metabolic syndrome ( MS) proposed by the IDF and revised NCEP have caused some confusion because patients have emerged that have satisfied the revised NCEP but not the IDF criteria. We performed this study to compare the prevalence of these criteria and to investigate the characteristics of discrepant cases.Research design and methods: A total of 7962 individuals aged X 20 years ( 3597 men; 4365 women) who participated in the 1998 Korean NHANES were included. We assessed the agreement between the revised NCEP and IDF criteria and investigated the characteristics of cases satisfying the revised NCEP criteria but not the IDF criteria.Results: The prevalence of MS by the revised NCEP (25.7% of men and 31.9% of women) was higher than that according to the IDF (14.2% of men and 26.6% of women). The IDF criteria failed to identify 44.9% of men and 16.6% of women identified as having MS according to the revised NCEP criteria. The discrepant group showed more adverse metabolic profiles and unfavorable lifestyles despite lower waist circumference as compared with those having MS by both the IDF and revised NCEP criteria. The prevalence of discrepant cases was higher among the elderly.Conclusions: The IDF criteria were inferior to the revised NCEP criteria in identifying the metabolically abnormal but nonobese groups known to be predisposed to type 2 diabetes and cardiovascular disease. Further research regarding the appropriateness of central obesity as an obligatory criterion proposed by the IDF seems to be warranted.