Intent to Receive Pandemic Influenza A (H1N1) Vaccine, Compliance with Social Distancing and Sources of Information in NC, 2009
Intent to Receive Pandemic Influenza A (H1N1) Vaccine, Compliance with Social Distancing and Sources of Information in NC, 2009
复制标题
DOI：
10.1371/journal.pone.0011226
复制
发表时间：
2010-06-18
期刊：
影响因子：
3.7
通讯作者：
MacDonald, Pia D. M.
中科院分区：
文献类型：
--
作者：
Horney, Jennifer A.;Moore, Zack;MacDonald, Pia D. M.
背景资料：尽管有安全有效的季节性疫苗，但公众对流感疫苗接种建议的遵守率很低，特别是在年轻人和2岁以下儿童中。在选定人群中，接受2009年甲型H1N1流感疫苗的意向估计为50%。这份报告措施的知识和意图，以接受大流行疫苗在人口为基础的设置，包括目标群体的季节性和H1N1 influenza.Methodology和主要调查结果：在2009年8月28日至29日，我们进行了一项以人口为基础的调查，在北卡罗来纳州的2个县。是项统计调查采用两阶段整群抽样方法，共抽样3067个住户，选出210个目标住户。估计患病率（PR）和95%置信区间（CI）。对甲型H1N1流感疫苗的了解程度较高，165人（80%）知道正在制备疫苗。共有133人（64%）打算接种大流行疫苗，134人（64%）打算接种季节性疫苗，109人（53%）打算接种两种疫苗。报告对H1N1感染的高度关注（PR 1.55; 95% CI：1.30，1.85），2008-09年接受季节性流感疫苗（PR 1.47; 95% CI：1.18，1.82），并打算在2009-10年接种季节性流感疫苗（PR 1.27; 95% CI：1.14，1.42）与接受大流行疫苗的意向相关。不相关的是疫苗知识，就业，有18岁以下的孩子，性别，种族/民族和年龄。不打算接种疫苗的理由包括没有感染的风险，担心疫苗的副作用，以及相信H1N1大流行引起的疾病是轻微的。45%的家庭与18岁以下的儿童和65%的工作的成年人报告的能力，以遵守自我隔离在家里7-10天，如果建议由authorisation.Conclusions和意义：这是第一次报告的人口为基础的快速评估，用于评估知识和意图，在社区样本中接受大流行疫苗。接种大流行性和季节性疫苗的意愿高于先前公布的报告。为了使不打算接种大流行性流感疫苗的人能够接触到这些人，公共卫生宣传应侧重于所认识到的感染风险和对疫苗安全性的关注。
Background: Public adherence to influenza vaccination recommendations has been low, particularly among younger adults and children under 2, despite the availability of safe and effective seasonal vaccine. Intention to receive 2009 pandemic influenza A (H1N1) vaccine has been estimated to be 50% in select populations. This report measures knowledge of and intention to receive pandemic vaccine in a population-based setting, including target groups for seasonal and H1N1 influenza.Methodology and Principal Findings: On August 28-29, 2009, we conducted a population-based survey in 2 counties in North Carolina. The survey used the 3067 two-stage cluster sampling methodology to identify 210 target households. Prevalence ratios (PR) and 95% confidence intervals (CI) were estimated. Knowledge of pandemic influenza A (H1N1) vaccine was high, with 165 (80%) aware that a vaccine was being prepared. A total of 133 (64%) respondents intended to receive pandemic vaccine, 134 (64%) intended to receive seasonal vaccine, and 109 (53%) intended to receive both. Reporting great concern about H1N1 infection (PR 1.55; 95% CI: 1.30, 1.85), receiving seasonal influenza vaccine in 2008-09 (PR 1.47; 95% CI: 1.18, 1.82), and intending to receive seasonal influenza vaccine in 2009-10 (PR 1.27; 95% CI: 1.14, 1.42) were associated with intention to receive pandemic vaccine. Not associated were knowledge of vaccine, employment, having children under age 18, gender, race/ethnicity and age. Reasons cited for not intending to get vaccinated include not being at risk for infection, concerns about vaccine side effects and belief that illness caused by pandemic H1N1 would be mild. Forty-five percent of households with children under 18 and 65% of working adults reported ability to comply with self-isolation at home for 7-10 days if recommended by authorities.Conclusions and Significance: This is the first report of a population based rapid assessment used to assess knowledge and intent to receive pandemic vaccine in a community sample. Intention to receive pandemic and seasonal vaccines was higher than previously published reports. To reach persons not intending to receive pandemic vaccine, public health communications should focus on the perceived risk of infection and concerns about vaccine safety.